Literature DB >> 11111926

LTK63 and LTR72, two mucosal adjuvants ready for clinical trials.

M Pizza1, M M Giuliani, M R Fontana, G Douce, G Dougan, R Rappuoli.   

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Year:  2000        PMID： 11111926     DOI： 10.1016/S1438-4221(00)80064-8

Source DB:  PubMed          Journal:  Int J Med Microbiol        ISSN： 1438-4221            Impact factor:   3.473


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  9 in total

1.  Induction of broad and potent anti-human immunodeficiency virus immune responses in rhesus macaques by priming with a DNA vaccine and boosting with protein-adsorbed polylactide coglycolide microparticles.

Authors:  Gillis Otten; Mary Schaefer; Catherine Greer; Maria Calderon-Cacia; Doris Coit; Jina Kazzaz; Angelica Medina-Selby; Mark Selby; Manmohan Singh; Mildred Ugozzoli; Jan zur Megede; Susan W Barnett; Derek O'Hagan; John Donnelly; Jeffrey Ulmer
Journal:  J Virol       Date:  2003-05       Impact factor: 5.103

2.  Genetic characterization and immunogenicity of coli surface antigen 4 from enterotoxigenic Escherichia coli when it is expressed in a Shigella live-vector strain.

Authors:  Zeev Altboum; Myron M Levine; James E Galen; Eileen M Barry
Journal:  Infect Immun       Date:  2003-03       Impact factor: 3.441

Review 3.  Developments in Vaccine Adjuvants.

Authors:  Farrhana Ziana Firdaus; Mariusz Skwarczynski; Istvan Toth
Journal:  Methods Mol Biol       Date:  2022

4.  Enhanced mucosal and systemic immune responses to Helicobacter pylori antigens through mucosal priming followed by systemic boosting immunizations.

Authors:  Michael Vajdy; Manmohan Singh; Mildred Ugozzoli; Maylene Briones; Elawati Soenawan; Lina Cuadra; Jina Kazzaz; Paolo Ruggiero; Samuele Peppoloni; Francesco Norelli; Giuseppe del Giudice; Derek O'Hagan
Journal:  Immunology       Date:  2003-09       Impact factor: 7.397

5.  An enzymatically active a domain is required for cholera-like enterotoxins to induce a long-lived blockade on the induction of oral tolerance: new method for screening mucosal adjuvants.

Authors:  Kenneth C Bagley; Sayed F Abdelwahab; Robert G Tuskan; George K Lewis
Journal:  Infect Immun       Date:  2003-12       Impact factor: 3.441

6.  Mucosal adjuvant properties of mutant LT-IIa and LT-IIb enterotoxins that exhibit altered ganglioside-binding activities.

Authors:  Hesham F Nawar; Sergio Arce; Michael W Russell; Terry D Connell
Journal:  Infect Immun       Date:  2005-03       Impact factor: 3.441

7.  The LTR72 mutant of heat-labile enterotoxin of Escherichia coli enhances the ability of peptide antigens to elicit CD4(+) T cells and secrete gamma interferon after coapplication onto bare skin.

Authors:  A-S Beignon; J-P Briand; R Rappuoli; S Muller; C D Partidos
Journal:  Infect Immun       Date:  2002-06       Impact factor: 3.441

8.  The catalytic A1 domains of cholera toxin and heat-labile enterotoxin are potent DNA adjuvants that evoke mixed Th1/Th17 cellular immune responses.

Authors:  Kenneth Bagley; Rong Xu; Ayuko Ota-Setlik; Michael Egan; Jennifer Schwartz; Timothy Fouts
Journal:  Hum Vaccin Immunother       Date:  2015       Impact factor: 3.452

9.  Intranasal immunization with pneumococcal conjugate vaccines with LT-K63, a nontoxic mutant of heat-Labile enterotoxin, as adjuvant rapidly induces protective immunity against lethal pneumococcal infections in neonatal mice.

Authors:  Håvard Jakobsen; Stefania Bjarnarson; Giuseppe Del Giudice; Monique Moreau; Claire-Anne Siegrist; Ingileif Jonsdottir
Journal:  Infect Immun       Date:  2002-03       Impact factor: 3.441
  9 in total

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