Pediatric reference values of estradiol, testosterone, lutropin, follitropin and prolactin.

Reference ranges for lutropin, follitropin, estradiol, testosterone, and prolactin were established by electrochemiluminescence immunoassays (Elecsys 2010, Roche Diagnostics) in 299 children of eight different age groups. The estradiol concentrations did not differ between the genders but dropped significantly in the first few months of life. The testosterone concentrations were higher in male than in female children, whereas the concentrations of follitropin were higher in female than in male children. The concentrations of lutropin were higher in male children (months 1-12) and higher in pubertal girls (years 13-20) in comparison to the corresponding age and gender.