| Literature DB >> 11109009 |
C Ballerini1, D Campani, G Rombolà, B Gran, B Nacmias, M P Amato, G Siracusa, L Bartolozzi, S Sorbi, L Massacesi.
Abstract
In this study we investigated the distribution of apolipoprotein E (APO E) genotypes in sporadic multiple sclerosis (MS) cases and in normal controls. Later onset of chronic progressive MS was observed in patients carrying the epsilon2 allele, whereas APO E alleles were found at similar frequency in MS and in the control population. These findings indicate that clinical heterogeneity, but probably not susceptibility to the disease, is associated to APO E genotypes.Entities:
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Year: 2000 PMID： 11109009 DOI： 10.1016/s0304-3940(00)01646-3
Source DB: PubMed Journal: Neurosci Lett ISSN： 0304-3940 Impact factor: 3.046