| Literature DB >> 11108644 |
R M Huggins1, N H Hoang, D Z Loesch.
Abstract
Longitudinal data from twin pairs may be used to determine how the genetic effects influencing a quantitative trait change with age. Here a model for mixed longitudinal data of Huggins and Loesch [1998] on unrelated individuals is extended to twin studies. The model is fitted using robust statistical methods and a bootstrap procedure is proposed to estimate the percentiles. The method is applied to longitudinal twin data on body mass index in male and female twin pairs aged 5-18 years. Copyright 2000 Wiley-Liss, Inc.Mesh:
Year: 2000 PMID: 11108644 DOI: 10.1002/1098-2272(200012)19:4<345::AID-GEPI6>3.0.CO;2-S
Source DB: PubMed Journal: Genet Epidemiol ISSN: 0741-0395 Impact factor: 2.135