Literature DB >> 11108642

Use of classification trees for association studies.

H Zhang1, G Bonney.   

Abstract

We propose the use of classification trees for association studies. This approach is applied to a data set from Genetic Analysis Workshop 9 (GAW9), and our analysis precisely identified two disease alleles. Our purpose is to demonstrate the great potential of tree-based analyses for genetic studies, and discuss some issues that warrant further investigation. Copyright 2000 Wiley-Liss, Inc.

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Year:  2000        PMID: 11108642     DOI: 10.1002/1098-2272(200012)19:4<323::AID-GEPI4>3.0.CO;2-5

Source DB:  PubMed          Journal:  Genet Epidemiol        ISSN: 0741-0395            Impact factor:   2.135


  56 in total

1.  Generalized T2 test for genome association studies.

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2.  Automated detection of informative combined effects in genetic association studies of complex traits.

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Review 4.  Large recursive partitioning analysis of complex disease pharmacogenetic studies. II. Statistical considerations.

Authors:  Dmitri V Zaykin; S Stanley Young
Journal:  Pharmacogenomics       Date:  2005-01       Impact factor: 2.533

5.  A forest-based approach to identifying gene and gene gene interactions.

Authors:  Xiang Chen; Ching-Ti Liu; Meizhuo Zhang; Heping Zhang
Journal:  Proc Natl Acad Sci U S A       Date:  2007-11-28       Impact factor: 11.205

6.  A partially linear tree-based regression model for multivariate outcomes.

Authors:  Kai Yu; William Wheeler; Qizhai Li; Andrew W Bergen; Neil Caporaso; Nilanjan Chatterjee; Jinbo Chen
Journal:  Biometrics       Date:  2009-05-07       Impact factor: 2.571

7.  Polymorphisms in TBX21 and STAT4 increase the risk of systemic sclerosis: evidence of possible gene-gene interaction and alterations in Th1/Th2 cytokines.

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Journal:  Arthritis Rheum       Date:  2009-12

8.  Tree-structured supervised learning and the genetics of hypertension.

Authors:  Jing Huang; Alfred Lin; Balasubramanian Narasimhan; Thomas Quertermous; C Agnes Hsiung; Low-Tone Ho; John S Grove; Michael Olivier; Koustubh Ranade; Neil J Risch; Richard A Olshen
Journal:  Proc Natl Acad Sci U S A       Date:  2004-07-12       Impact factor: 11.205

9.  FastChi: an efficient algorithm for analyzing gene-gene interactions.

Authors:  Xiang Zhang; Fei Zou; Wei Wang
Journal:  Pac Symp Biocomput       Date:  2009

10.  Genetic variations in cell-cycle pathway and the risk of oral premalignant lesions.

Authors:  Yuanqing Ye; Scott M Lippman; J Jack Lee; Meng Chen; Marsha L Frazier; Margaret R Spitz; Xifeng Wu
Journal:  Cancer       Date:  2008-11-01       Impact factor: 6.860

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