Literature DB >> 11108150

Mechanisms of angiotensin II-induced platelet-derived growth factor gene expression.

L M Khachigian1, Y Takuwa, T Collins.   

Abstract

Angiotensin II induces the expression of platelet-derived growth factor A-chain and B-chain in cultured vascular smooth muscle cells at the level of transcription. The renin-angiotensin system has also been implicated in the increased expression of platelet-derived growth factor in the mechanically-injured artery wall. This review is concerned with recent developments in our understanding of the signaling and transcriptional mechanisms mediating the inducible expression of one vasoconstrictor by another.

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Year:  2000        PMID： 11108150

Source DB:  PubMed          Journal:  Mol Cell Biochem        ISSN： 0300-8177            Impact factor:   3.396


  35 in total

1.  Stimulated activation of platelet-derived growth factor receptor in vivo in balloon-injured arteries: a link between angiotensin II and intimal thickening.

Authors:  J Abe; J Deguchi; T Matsumoto; N Takuwa; M Noda; M Ohno; M Makuuchi; K Kurokawa; Y Takuwa
Journal:  Circulation       Date:  1997-09-16       Impact factor: 29.690

2.  Angiotensin II stimulates platelet-derived growth factor-B chain expression in newborn rat vascular smooth muscle cells and neointimal cells through Ras, extracellular signal-regulated protein kinase, and c-Jun N-terminal protein kinase mechanisms.

Authors:  J Deguchi; M Makuuchi; T Nakaoka; T Collins; Y Takuwa
Journal:  Circ Res       Date:  1999-10-01       Impact factor: 17.367

3.  Overexpression of human endothelial nitric oxide synthase in rat vascular smooth muscle cells and in balloon-injured carotid artery.

Authors:  L Chen; G Daum; R Forough; M Clowes; U Walter; A W Clowes
Journal:  Circ Res       Date:  1998-05-04       Impact factor: 17.367

4.  Human endothelial nitric oxide synthase gene transfer inhibits vascular smooth muscle cell proliferation and neointima formation after balloon injury in rats.

Authors:  S Janssens; D Flaherty; Z Nong; O Varenne; N van Pelt; C Haustermans; P Zoldhelyi; R Gerard; D Collen
Journal:  Circulation       Date:  1998-04-07       Impact factor: 29.690

5.  Different functions of the platelet-derived growth factor-alpha and -beta receptors for the migration and proliferation of cultured baboon smooth muscle cells.

Authors:  N Koyama; C E Hart; A W Clowes
Journal:  Circ Res       Date:  1994-10       Impact factor: 17.367

Review 6.  Early growth response protein 1 (Egr-1): prototype of a zinc-finger family of transcription factors.

Authors:  A Gashler; V P Sukhatme
Journal:  Prog Nucleic Acid Res Mol Biol       Date:  1995

7.  Characterization of cloned aortic smooth muscle cells from young rats.

Authors:  J M Lemire; C W Covin; S White; C M Giachelli; S M Schwartz
Journal:  Am J Pathol       Date:  1994-05       Impact factor: 4.307

8.  FK409, a new nitric-oxide donor, suppresses smooth muscle proliferation in the rat model of balloon angioplasty.

Authors:  J Seki; M Nishio; Y Kato; Y Motoyama; K Yoshida
Journal:  Atherosclerosis       Date:  1995-09       Impact factor: 5.162

9.  Vascular injury induces angiotensinogen gene expression in the media and neointima.

Authors:  H Rakugi; H J Jacob; J E Krieger; J R Ingelfinger; R E Pratt
Journal:  Circulation       Date:  1993-01       Impact factor: 29.690

10.  Rat carotid neointimal smooth muscle cells reexpress a developmentally regulated mRNA phenotype during repair of arterial injury.

Authors:  M W Majesky; C M Giachelli; M A Reidy; S M Schwartz
Journal:  Circ Res       Date:  1992-10       Impact factor: 17.367
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  2 in total

1.  Blockage of angiotensin II type I receptor decreases the synthesis of growth factors and induces apoptosis in C6 cultured cells and C6 rat glioma.

Authors:  O Arrieta; P Guevara; E Escobar; R García-Navarrete; B Pineda; J Sotelo
Journal:  Br J Cancer       Date:  2005-04-11       Impact factor: 7.640

2.  Expression of AT1 and AT2 angiotensin receptors in astrocytomas is associated with poor prognosis.

Authors:  O Arrieta; B Pineda-Olvera; P Guevara-Salazar; N Hernández-Pedro; D Morales-Espinosa; T L Cerón-Lizarraga; C H González-De la Rosa; D Rembao; B Segura-Pacheco; J Sotelo
Journal:  Br J Cancer       Date:  2008-07-08       Impact factor: 7.640
  2 in total

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