Literature DB >> 11104397

Perspectives on modern orthopaedics: use of Adcon-L for epidural scar prevention.

J S Fischgrund1.   

Abstract

Adcon-L is a biodegradable gel matrix that was recently approved by the Food and Drug Administration for use during single-level posterior lumbar laminectomy or laminotomy procedures. Experimental and clinical studies have suggested that the use of this product will decrease postoperative epidural scarring. However, the relationship between epidural fibrosis and patient outcome remains unclear. If the treating surgeon is of the opinion that there is a need to reduce epidural scar, the use of this product appears worthwhile. However, further studies are needed to evaluate clinical outcome and justify the use of this product on a routine basis.

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Year:  2000        PMID: 11104397     DOI: 10.5435/00124635-200011000-00001

Source DB:  PubMed          Journal:  J Am Acad Orthop Surg        ISSN: 1067-151X            Impact factor:   3.020


  6 in total

1.  Reduction of adhesion formation and promotion of wound healing after laminectomy by pharmacological inhibition of pro-inflammatory cytokines: an experimental study in the rat.

Authors:  Kjell Olmarker
Journal:  Eur Spine J       Date:  2010-07-10       Impact factor: 3.134

2.  Anti-adhesive effect of poloxamer-based thermo-sensitive sol-gel in rabbit laminectomy model.

Authors:  Sung Joon Shin; Jae Hyup Lee; Jungwon So; Kyungdan Min
Journal:  J Mater Sci Mater Med       Date:  2016-09-19       Impact factor: 3.896

3.  Implantation of amniotic membrane to reduce postlaminectomy epidural adhesions.

Authors:  Huiren Tao; Hongbin Fan
Journal:  Eur Spine J       Date:  2009-04-30       Impact factor: 3.134

Review 4.  [Post disc surgery syndrome: indications for surgery and conservative and operative treatment possibilities].

Authors:  A Krödel
Journal:  Orthopade       Date:  2008-04       Impact factor: 1.087

5.  The Effects of Rifampin, Povidone-Iodine and Hydrogen Peroxide on the Formation of Epidural Fibrosis in the Experimental Epidural Fibrosis Model.

Authors:  Zahir Kizilay; Nesibe Kahraman Cetin; Özgur İsmailoglu; Ali Yılmaz; İmran Kurt Omurlu; Mehmet Erdal Coskun; Serdar Aktaş
Journal:  Inflammation       Date:  2016-08       Impact factor: 4.092

6.  Quercetin inhibits fibroblasts proliferation and reduces surgery-induced epidural fibrosis via the autophagy-mediated PI3K/Akt/mTOR pathway.

Authors:  Yile Cao; Hui Chen; Yu Sun; Zhehao Fan; Hong Cheng
Journal:  Bioengineered       Date:  2022-04       Impact factor: 6.832

  6 in total

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