P H St George-Hyslop1. Show Affiliations » 1. Center for Research in Neurodegenerative Diseases, University of Toronto.
Abstract
Entities: Disease
Mesh： See more » Alzheimer Disease/etiologyAlzheimer Disease/geneticsAlzheimer Disease/pathologyAlzheimer Disease/therapyAmyloid Precursor Protein SecretasesAmyloid beta-Peptides/chemistryAmyloid beta-Protein Precursor/chemistryAmyloid beta-Protein Precursor/geneticsAnimalsAspartic Acid Endopeptidases/chemistryBrain Chemistry/geneticsBrain Chemistry/physiologyEndopeptidasesFemaleHumansMaleMembrane Proteins/chemistryMembrane Proteins/geneticsMiceMicrotubules/chemistryMicrotubules/pathologyMutationNeurofibrillary Tangles/chemistryNeurons/pathologyPlaque, Amyloid/chemistryPlaque, Amyloid/pathologyPresenilin-1Presenilin-2tau Proteins/chemistry
Substances： See more » Amyloid beta-PeptidesAmyloid beta-Protein PrecursorMembrane ProteinsPSEN1 protein, humanPSEN2 protein, humanPresenilin-1Presenilin-2tau ProteinsAmyloid Precursor Protein SecretasesEndopeptidasesAspartic Acid EndopeptidasesBACE2 protein, humanBACE1 protein, humanBace1 protein, mouse
Year: 2000 PMID： 11103462 DOI： 10.1038/scientificamerican1200-76
Source DB: PubMed Journal: Sci Am ISSN： 0036-8733 Impact factor: 2.142