Literature DB >> 11102867

Dissecting and manipulating the pathway for glycosylphos-phatidylinositol-anchor biosynthesis.

T Kinoshita1, N Inoue.   

Abstract

The pathway for glycosylphosphatidylinositol-anchor biosynthesis consists of at least 10 reaction steps. Many of the genes encoding the enzymes and regulators involved in this pathway have been recently cloned and their products characterised. These studies have revealed the common and also different characteristics of glycosylphosphatidyl-inositol biosynthesis enzymes in different organisms, leading to the development of species-specific inhibitors of the pathway.

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Year:  2000        PMID: 11102867     DOI: 10.1016/s1367-5931(00)00151-4

Source DB:  PubMed          Journal:  Curr Opin Chem Biol        ISSN: 1367-5931            Impact factor:   8.822


  65 in total

1.  Specificity of GlcNAc-PI de-N-acetylase of GPI biosynthesis and synthesis of parasite-specific suicide substrate inhibitors.

Authors:  T K Smith; A Crossman; C N Borissow; M J Paterson; A Dix; J S Brimacombe; M A Ferguson
Journal:  EMBO J       Date:  2001-07-02       Impact factor: 11.598

2.  Synthetic Studies of Glycosylphosphatidylinositol (GPI) Anchors and GPI-Anchored Peptides, Glycopeptides, and Proteins.

Authors:  Zhongwu Guo
Journal:  Curr Org Synth       Date:  2013-06-01       Impact factor: 1.975

Review 3.  Recent progress in synthetic and biological studies of GPI anchors and GPI-anchored proteins.

Authors:  Shichong Yu; Zhongwu Guo; Charlie Johnson; Guofeng Gu; Qiuye Wu
Journal:  Curr Opin Chem Biol       Date:  2013-10-12       Impact factor: 8.822

4.  Catalysis by N-acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase (PIG-L) from Entamoeba histolytica: new roles for conserved residues.

Authors:  Mohammad Ashraf; Perinthottathil Sreejith; Usha Yadav; Sneha Sudha Komath
Journal:  J Biol Chem       Date:  2013-01-22       Impact factor: 5.157

Review 5.  Chemical synthesis of glycosylphosphatidylinositol anchors.

Authors:  Benjamin M Swarts; Zhongwu Guo
Journal:  Adv Carbohydr Chem Biochem       Date:  2012       Impact factor: 12.200

6.  Saccharomyces cerevisiae CWH43 is involved in the remodeling of the lipid moiety of GPI anchors to ceramides.

Authors:  Mariko Umemura; Morihisa Fujita; Takehiko Yoko-O; Akiyoshi Fukamizu; Yoshifumi Jigami
Journal:  Mol Biol Cell       Date:  2007-08-29       Impact factor: 4.138

7.  Glycosylphosphatidylinositol lipid anchoring of plant proteins. Sensitive prediction from sequence- and genome-wide studies for Arabidopsis and rice.

Authors:  Birgit Eisenhaber; Michael Wildpaner; Carolyn J Schultz; Georg H H Borner; Paul Dupree; Frank Eisenhaber
Journal:  Plant Physiol       Date:  2003-12       Impact factor: 8.340

8.  PIG-W is critical for inositol acylation but not for flipping of glycosylphosphatidylinositol-anchor.

Authors:  Yoshiko Murakami; Uamporn Siripanyapinyo; Yeongjin Hong; Ji Young Kang; Sonoko Ishihara; Hideki Nakakuma; Yusuke Maeda; Taroh Kinoshita
Journal:  Mol Biol Cell       Date:  2003-06-13       Impact factor: 4.138

9.  Intracellular glycosylphosphatidylinositols accumulate on endosomes: toxicity of alpha-toxin to Leishmania major.

Authors:  Zhifeng Zheng; Rodney K Tweten; Kojo Mensa-Wilmot
Journal:  Eukaryot Cell       Date:  2005-03

10.  Yeast ARV1 is required for efficient delivery of an early GPI intermediate to the first mannosyltransferase during GPI assembly and controls lipid flow from the endoplasmic reticulum.

Authors:  Kentaro Kajiwara; Reika Watanabe; Harald Pichler; Kensuke Ihara; Suguru Murakami; Howard Riezman; Kouichi Funato
Journal:  Mol Biol Cell       Date:  2008-02-20       Impact factor: 4.138

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