Literature DB >> 11102825

Evolutionary genetics: what is driving male mutation?

G McVean1.   

Abstract

In mammals, most new mutations occur in males. But a study of the evolution of a human X to Y chromosomal translocation has revealed a sex bias much lower than previous estimates. Patterns of substitution suggest that differential methylation between male and female germ lines is a key determinant of the mutation rate.

Entities:  

Mesh:

Year:  2000        PMID: 11102825     DOI: 10.1016/s0960-9822(00)00787-9

Source DB:  PubMed          Journal:  Curr Biol        ISSN: 0960-9822            Impact factor:   10.834


  1 in total

1.  Mutation accumulation and fitness effects in hybridogenetic populations: a comparison to sexual and asexual systems.

Authors:  Christian Som; Homayoun C Bagheri; Heinz-Ulrich Reyer
Journal:  BMC Evol Biol       Date:  2007-05-21       Impact factor: 3.260

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.