| Literature DB >> 11100129 |
B Prakken1, M Wauben, D Genini, R Samodal, J Barnett, A Mendivil, L Leoni, S Albani.
Abstract
Recent progress in molecular medicine has provided important tools to identify antigen-specific T cells. In most cases, the approach is based on oligomeric combinations of recombinant major histocompatibility complex-peptide complexes fixed to various rigid supports available for binding by the T-cell receptor. These tools have greatly increased our insight into mechanisms of immune responses mediated by CD8+ T cells. Examples of the diverse fields of application for this technology include immunization, viral infections and oral tolerance induction.Entities:
Mesh:
Substances:
Year: 2000 PMID: 11100129 DOI: 10.1038/82231
Source DB: PubMed Journal: Nat Med ISSN: 1078-8956 Impact factor: 53.440