| Literature DB >> 11097058 |
G M Bonora1, A M De Franco, R Rossin, F M Veronese, P Ferruti, O Plyasunova, P E Vorobjev, D V Pyshnyi, N I Komarova, V F Zarytova.
Abstract
A new amphiphilic, high-molecular weight poly (N-acryloylmorpholine) (PAcM) polymer has been used to be linked to oligonucleotide chains through a liquid-phase stepwise synthesis. This new conjugate has been investigated for its melting property, nuclease stability and capacity to elicit RNase H activity. Its antisense activity against an HIV-1 target has been also evaluated.Entities:
Mesh：
Substances：
Year: 2000 PMID： 11097058 DOI： 10.1080/15257770008033051
Source DB: PubMed Journal: Nucleosides Nucleotides Nucleic Acids ISSN： 1525-7770 Impact factor: 1.381