Literature DB >> 1109705

Early changes in lung water after haemorrhagic shock in pigs and dogs.

W H Noble.   

Abstract

This study has demonstrated a 34 per cent rise in lung water after shock and retransfusion of blood. This extra lung water was associated with increased pulmonary artery pressure, increased plumonary vascular resistance and reduced myocardial performance. These findings occurred despite the failure of arterial pressure to return to normal after retransfusion blood. Although this increased lung water is less than anything which can be detected clinically it may represent the beginnings of the shock lung syndrome as oedema progresses over period of weeks. A reasonable approach to the problem should include attempts to reduce the elevated plumonary vascular resistance. NaHCO3 should be infused before or during administration of the first bottle of blood in an attempt to improve myocardial function and reduce pulmonary vascular resistance. Fluids should not be infused simply to return arterial pressures in the pulmonary vascular bed. Pulmonary artery and wedge pressure monitoring with Swan Ganz catheters may improve the management of shock patients.

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Year:  1975        PMID: 1109705     DOI: 10.1007/bf03004817

Source DB:  PubMed          Journal:  Can Anaesth Soc J        ISSN: 0008-2856


  7 in total

1.  Fine structural changes in haemodynamic pulmonary oedema.

Authors:  W H Noble; K Kovacs; J C Kay
Journal:  Can Anaesth Soc J       Date:  1974-05

Review 2.  Pulmonary involvement in hypovolemic shock.

Authors:  G S Moss
Journal:  Annu Rev Med       Date:  1972       Impact factor: 13.739

3.  A new technique for measuring pulmonary edema.

Authors:  W H Noble; J Obdrzalek; J C Kay
Journal:  J Appl Physiol       Date:  1973-04       Impact factor: 3.531

4.  Thermal and conductivity dilution curves for rapid quantitation of pulmonary edema.

Authors:  W H Noble; J W Severinghaus
Journal:  J Appl Physiol       Date:  1972-06       Impact factor: 3.531

5.  Role of the acidosis in the development of increased pulmonary vascular resistance and shock lung in experimental hemorrhagic shock.

Authors:  S I Kim; W C Shoemaker
Journal:  Surgery       Date:  1973-05       Impact factor: 3.982

6.  The mechanism of pulmonary damage following traumatic shock.

Authors:  F W Blaisdell; R J Stallone
Journal:  Surg Gynecol Obstet       Date:  1970-01

7.  The adult acute respiratory insufficiency syndrome following nonthoracic trauma: the lung in shock.

Authors:  E H Bergofsky
Journal:  Am J Cardiol       Date:  1970-12       Impact factor: 2.778

  7 in total
  4 in total

1.  Pulmonary vascular effects of acetylsalicylic acid, chloroquine, dextran and methylprednisolone given after haemorrhagic shock in dogs.

Authors:  W H Noble; C E Famewo; M B Garvey
Journal:  Can Anaesth Soc J       Date:  1977-11

Review 2.  Pulmonary oedema: a review.

Authors:  W H Noble
Journal:  Can Anaesth Soc J       Date:  1980-05

3.  Hypoxaemia created by pulmonary oedema after pulmonary microemboli in dogs.

Authors:  R Martineau; W H Noble
Journal:  Can Anaesth Soc J       Date:  1983-03

4.  Comparison of lung injury after normal or small volume optimized resuscitation in a model of hemorrhagic shock.

Authors:  Antoine Roch; Dorothée Blayac; Patrice Ramiara; Bruno Chetaille; Valérie Marin; Pierre Michelet; Dominique Lambert; Laurent Papazian; Jean-Pierre Auffray; Jean-Pierre Carpentier
Journal:  Intensive Care Med       Date:  2007-05-31       Impact factor: 17.440

  4 in total

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