Literature DB >> 11095579

Pharmacogenetics of the arylamine N-acetyltransferases: a symposium in honor of Wendell W. Weber.

D W Hein1, C A McQueen, D M Grant, G H Goodfellow, F F Kadlubar, W W Weber.   

Abstract

This article is a report on a symposium sponsored by the American Society for Pharmacology and Experimental Therapeutics presented at the joint meeting of the American Society for Biochemistry and Molecular Biology and the American Society for Pharmacology and Experimental Therapeutics, June 4-8, Boston, Massachusetts. The presentations focused on the pharmacogenetics of the NAT1 and NAT2 arylamine N-acetyltransferases, including developmental regulation, structure-function relationships, and their possible role in susceptibility to breast, colon, and pancreatic cancers. The symposium honored Wendell W. Weber for over 35 years of leadership and scientific advancement in pharmacogenetics and was highlighted by his overview of the historical development of the field.

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Year:  2000        PMID： 11095579

Source DB:  PubMed          Journal:  Drug Metab Dispos        ISSN： 0090-9556            Impact factor:   3.922


  17 in total

1.  Purification, crystallization and preliminary X-ray characterization of Bacillus cereus arylamine N-acetyltransferase 3 [(BACCR)NAT3].

Authors:  Xavier Kubiak; Benjamin Pluvinage; Inès Li de la Sierra-Gallay; Patrick Weber; Ahmed Haouz; Jean-Marie Dupret; Fernando Rodrigues-Lima
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2012-01-26

2.  Human N-acetyltransferase 1 *10 and *11 alleles increase protein expression through distinct mechanisms and associate with sulfamethoxazole-induced hypersensitivity.

Authors:  Danxin Wang; Michael F Para; Susan L Koletar; Wolfgang Sadee
Journal:  Pharmacogenet Genomics       Date:  2011-10       Impact factor: 2.089

3.  Lack of association of the N-acetyltransferase NAT1*10 allele with prostate cancer incidence, grade, or stage among smokers in Finland.

Authors:  LaCreis R Kidd; David W Hein; Karen Woodson; Philip R Taylor; Demetrius Albanes; Jarmo Virtamo; Joseph A Tangrea
Journal:  Biochem Genet       Date:  2010-10-08       Impact factor: 1.890

4.  Identification of N-acetyltransferase 2 (NAT2) transcription start sites and quantitation of NAT2-specific mRNA in human tissues.

Authors:  Anwar Husain; Xiaoyan Zhang; Mark A Doll; J Christopher States; David F Barker; David W Hein
Journal:  Drug Metab Dispos       Date:  2007-02-07       Impact factor: 3.922

5.  Modification by N-acetyltransferase 1 genotype on the association between dietary heterocyclic amines and colon cancer in a multiethnic study.

Authors:  Lesley M Butler; Robert C Millikan; Rashmi Sinha; Temitope O Keku; Scott Winkel; Brent Harlan; Allison Eaton; Marilie D Gammon; Robert S Sandler
Journal:  Mutat Res       Date:  2007-10-13       Impact factor: 2.433

Review 6.  N-acetyltransferase SNPs: emerging concepts serve as a paradigm for understanding complexities of personalized medicine.

Authors:  David W Hein
Journal:  Expert Opin Drug Metab Toxicol       Date:  2009-04       Impact factor: 4.481

7.  Crystallization and preliminary X-ray characterization of arylamine N-acetyltransferase C (BanatC) from Bacillus anthracis.

Authors:  Benjamin Pluvinage; Inés Li de la Sierra-Gallay; Marta Martins; Nilusha Ragunathan; Jean-Marie Dupret; Fernando Rodrigues-Lima
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2007-09-19

8.  Human disposition, metabolism and excretion of etamicastat, a reversible, peripherally selective dopamine β-hydroxylase inhibitor.

Authors:  Ana I Loureiro; Jose F Rocha; Carlos Fernandes-Lopes; Teresa Nunes; Lyndon C Wright; Luis Almeida; Patricio Soares-da-Silva
Journal:  Br J Clin Pharmacol       Date:  2014-06       Impact factor: 4.335

9.  Hair dye use, genetic variation in N-acetyltransferase 1 (NAT1) and 2 (NAT2), and risk of non-Hodgkin lymphoma.

Authors:  Lindsay M Morton; Leslie Bernstein; Sophia S Wang; David W Hein; Nathaniel Rothman; Joanne S Colt; Scott Davis; James R Cerhan; Richard K Severson; Robert Welch; Patricia Hartge; Shelia Hoar Zahm
Journal:  Carcinogenesis       Date:  2007-05-23       Impact factor: 4.944

10.  Meat intake, heterocyclic amine exposure, and metabolizing enzyme polymorphisms in relation to colorectal polyp risk.

Authors:  Aesun Shin; Martha J Shrubsole; Jeffrey M Rice; Qiuyin Cai; Mark A Doll; Jirong Long; Walter E Smalley; Yu Shyr; Rashmi Sinha; Reid M Ness; David W Hein; Wei Zheng
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2008-02       Impact factor: 4.254
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