Extraosseous Ewing sarcoma of the vagina.

BACKGROUND: Ewing sarcoma is a highly malignant childhood bone neoplasm. Extraosseous presentations of Ewing sarcomas include the trunk, extremities, uterus, cervix, and vagina. CASE: A 35-year-old woman, gravida 3, para 3, presented with a painless vaginal mass. After surgical excision, pathology results diagnosed an extraosseous Ewing sarcoma. Chemotherapy was given, followed by external beam and vaginal intracavitary brachytherapy, then more chemotherapy. After 48 months post-treatment, there is no clinical evidence of recurrence.
CONCLUSION: Although rare, Ewing sarcoma can present as a vaginal mass.