Literature DB >> 11093699

Rapid access to uronic acid-based mimetics of Kdn2en from D-glucurono-6,3-lactone.

P Florio1, R J Thomson, M von Itzstein.   

Abstract

A concise route to novel mimetics of Kdn2en, based on delta4-uronic acids, from D-glucurono-6,3-lactone is presented. Uronic acid-based mimetics in which an aliphatic ether (O-glycoside), a thioether (S-glycoside), or acetamide takes the place of the natural C-6 glycerol sidechain of the sialic acid were synthesized from the key intermediate, methyl 2,3,4-tri-O-acetyl-alpha-D-glucopyranosyluronate bromide.

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Year:  2000        PMID: 11093699     DOI: 10.1016/s0008-6215(00)00228-7

Source DB:  PubMed          Journal:  Carbohydr Res        ISSN: 0008-6215            Impact factor:   2.104


  2 in total

1.  Synthesis and antiviral activities of spacer-linked 1-thioglucuronide analogues of glycyrrhizin.

Authors:  Christian Stanetty; Andrea Wolkerstorfer; Hassan Amer; Andreas Hofinger; Ulrich Jordis; Dirk Claßen-Houben; Paul Kosma
Journal:  Beilstein J Org Chem       Date:  2012-05-08       Impact factor: 2.883

2.  Design, synthesis and DNA interaction study of new potential DNA bis-intercalators based on glucuronic acid.

Authors:  Jiuyang Zhao; Wei Li; Rui Ma; Shaopeng Chen; Sumei Ren; Tao Jiang
Journal:  Int J Mol Sci       Date:  2013-08-15       Impact factor: 5.923

  2 in total

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