| Literature DB >> 11093699 |
P Florio1, R J Thomson, M von Itzstein.
Abstract
A concise route to novel mimetics of Kdn2en, based on delta4-uronic acids, from D-glucurono-6,3-lactone is presented. Uronic acid-based mimetics in which an aliphatic ether (O-glycoside), a thioether (S-glycoside), or acetamide takes the place of the natural C-6 glycerol sidechain of the sialic acid were synthesized from the key intermediate, methyl 2,3,4-tri-O-acetyl-alpha-D-glucopyranosyluronate bromide.Entities:
Mesh:
Substances:
Year: 2000 PMID: 11093699 DOI: 10.1016/s0008-6215(00)00228-7
Source DB: PubMed Journal: Carbohydr Res ISSN: 0008-6215 Impact factor: 2.104