Literature DB >> 11093398

Squamous cell carcinoma of the nasal planum in 17 dogs.

B D Lascelles1, A T Parry, M F Stidworthy, J M Dobson, R A White.   

Abstract

Squamous cell carcinoma of the nasal planum was diagnosed in 17 dogs over a period of 11 years. Ulceration, bleeding and sneezing were the most common clinical signs. One dog had cytological evidence of metastasis to the local lymph node. The dogs were treated by surgical resection, fractionated megavoltage irradiation, or a combination of the two. Surgical resection gave the most favourable results; four of six dogs were cured but a recurrence of the tumour was predicted in the other two on the basis of incomplete or marginal resection. Radiotherapy alone was not as effective; one of four dogs was cured, and the tumour recurred in the others within 24 weeks (median eight weeks). Combined surgical resection and radiotherapy did not produce a cure in any of the seven remaining dogs, and the tumour recurred within 12 weeks (median nine weeks). Three dogs had cytological evidence of lymph node metastasis when the tumour recurred. The dogs' prognosis was adversely affected by the interval between their initial examination and treatment, but there was no apparent association between the histological grade of the tumour and the clinical outcome.

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Year:  2000        PMID: 11093398     DOI: 10.1136/vr.147.17.473

Source DB:  PubMed          Journal:  Vet Rec        ISSN: 0042-4900            Impact factor:   2.695


  3 in total

1.  Spontaneous Development of Cutaneous Squamous Cell Carcinoma in Mice with Cell-specific Deletion of Inhibitor of κB Kinase 2.

Authors:  Kelly S Kirkley; Kelly D Walton; Colleen Duncan; Ronald B Tjalkens
Journal:  Comp Med       Date:  2017-10-01       Impact factor: 0.982

2.  Outcome and complication rate of nasal planectomy reconstructed with direct mucocutaneous apposition.

Authors:  Madeline J Edgar; Mariana T Quina; Cheryl A Tano; Christopher P Bloch
Journal:  Can Vet J       Date:  2022-04       Impact factor: 1.075

3.  Cyto-histopathological and outcome features of the prepuce squamous cell carcinoma of a mixed breed dog.

Authors:  Javad Yaghoobi Yeganeh Manesh; Radmehr Shafiee; Ali Mohammad Bahrami; Mehdi Pourzaer; Maryam Pourzaer; Behnam Pedram; Javad Javanbakht; Aram Mokarizadeh; Farshid Khadivar
Journal:  Diagn Pathol       Date:  2014-06-06       Impact factor: 2.644

  3 in total

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