Literature DB >> 11092939

Crystallization of the catalytic domain of murine terminal deoxynucleotidyl transferase.

N Sukumar1, J B Boulé, N Expert-Bezançon, N Jourdan, J Lescar, F Rougeon, C Papanicolaou, M Delarue.   

Abstract

The catalytic domain of murine terminal deoxynucleotidyl transferase (TdT) has been crystallized in the space group P2(1)2(1)2(1), with unit-cell parameters a = 47.1, b = 86.2, c = 111.7 A. The crystals diffract to a resolution of 2.4 A using synchrotron radiation and a full data set has been collected from the native crystals. The enzyme was shown to be active in the crystalline state.

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Year:  2000        PMID: 11092939     DOI: 10.1107/s090744490001297x

Source DB:  PubMed          Journal:  Acta Crystallogr D Biol Crystallogr        ISSN: 0907-4449


  2 in total

1.  Crystal structures of a template-independent DNA polymerase: murine terminal deoxynucleotidyltransferase.

Authors:  M Delarue; J B Boulé; J Lescar; N Expert-Bezançon; N Jourdan; N Sukumar; F Rougeon; C Papanicolaou
Journal:  EMBO J       Date:  2002-02-01       Impact factor: 11.598

2.  Conferring a template-dependent polymerase activity to terminal deoxynucleotidyltransferase by mutations in the Loop1 region.

Authors:  Félix Romain; Isabelle Barbosa; Jérôme Gouge; François Rougeon; Marc Delarue
Journal:  Nucleic Acids Res       Date:  2009-06-05       Impact factor: 16.971

  2 in total

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