Literature DB >> 11092872

Transcription activation by a variety of AraC/XylS family activators does not depend on the class II-specific activation determinant in the N-terminal domain of the RNA polymerase alpha subunit.

S M Egan1, A J Pease, J Lang, X Li, V Rao, W K Gillette, R Ruiz, J L Ramos, R E Wolf.   

Abstract

The N-terminal domain of the RNA polymerase alpha subunit (alpha-NTD) was tested for a role in transcription activation by a variety of AraC/XylS family members. Based on substitutions at residues 162 to 165 and an extensive genetic screen we conclude that alpha-NTD is not an activation target for these activators.

Mesh：

Substances：

Year:  2000        PMID： 11092872      PMCID： PMC94837          DOI： 10.1128/JB.182.24.7075-7077.2000

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  30 in total

1.  Structural requirements for marbox function in transcriptional activation of mar/sox/rob regulon promoters in Escherichia coli: sequence, orientation and spatial relationship to the core promoter.

Authors:  R G Martin; W K Gillette; S Rhee; J L Rosner
Journal:  Mol Microbiol       Date:  1999-11       Impact factor: 3.501

2.  Genetic evidence that transcription activation by RhaS involves specific amino acid contacts with sigma 70.

Authors:  P M Bhende; S M Egan
Journal:  J Bacteriol       Date:  2000-09       Impact factor: 3.490

3.  Transcription from the rha operon psr promoter.

Authors:  J F Tobin; R F Schleif
Journal:  J Mol Biol       Date:  1990-01-05       Impact factor: 5.469

4.  Altered effector specificities in regulators of gene expression: TOL plasmid xylS mutants and their use to engineer expansion of the range of aromatics degraded by bacteria.

Authors:  J L Ramos; A Stolz; W Reineke; K N Timmis
Journal:  Proc Natl Acad Sci U S A       Date:  1986-11       Impact factor: 11.205

5.  The presence of two complete homologous meta pathway operons on TOL plasmid pWW53.

Authors:  D J Osborne; R W Pickup; P A Williams
Journal:  J Gen Microbiol       Date:  1988-11

6.  Differential expression of over 60 chromosomal genes in Escherichia coli by constitutive expression of MarA.

Authors:  T M Barbosa; S B Levy
Journal:  J Bacteriol       Date:  2000-06       Impact factor: 3.490

7.  Purification and properties of RhaR, the positive regulator of the L-rhamnose operons of Escherichia coli.

Authors:  J F Tobin; R F Schleif
Journal:  J Mol Biol       Date:  1990-01-05       Impact factor: 5.469

8.  Roles of cyclic AMP receptor protein and the carboxyl-terminal domain of the alpha subunit in transcription activation of the Escherichia coli rhaBAD operon.

Authors:  C C Holcroft; S M Egan
Journal:  J Bacteriol       Date:  2000-06       Impact factor: 3.490

9.  Amino acid-DNA contacts by RhaS: an AraC family transcription activator.

Authors:  P M Bhende; S M Egan
Journal:  J Bacteriol       Date:  1999-09       Impact factor: 3.490

10.  Regulator and enzyme specificities of the TOL plasmid-encoded upper pathway for degradation of aromatic hydrocarbons and expansion of the substrate range of the pathway.

Authors:  M A Abril; C Michan; K N Timmis; J L Ramos
Journal:  J Bacteriol       Date:  1989-12       Impact factor: 3.490
View more
  9 in total

Review 1.  Growing repertoire of AraC/XylS activators.

Authors:  Susan M Egan
Journal:  J Bacteriol       Date:  2002-10       Impact factor: 3.490

2.  Mechanism of ToxT-dependent transcriptional activation at the Vibrio cholerae tcpA promoter.

Authors:  Robin R Hulbert; Ronald K Taylor
Journal:  J Bacteriol       Date:  2002-10       Impact factor: 3.490

Review 3.  Bacterial transcriptional regulators for degradation pathways of aromatic compounds.

Authors:  David Tropel; Jan Roelof van der Meer
Journal:  Microbiol Mol Biol Rev       Date:  2004-09       Impact factor: 11.056

4.  ExsA recruits RNA polymerase to an extended -10 promoter by contacting region 4.2 of sigma-70.

Authors:  Christopher A Vakulskas; Evan D Brutinel; Timothy L Yahr
Journal:  J Bacteriol       Date:  2010-05-07       Impact factor: 3.490

5.  Allosteric regulation within the highly interconnected structural scaffold of AraC/XylS homologs tolerates a wide range of amino acid changes.

Authors:  Hunter R Picard; Kristen S Schwingen; Lisa M Green; David L Shis; Susan M Egan; Matthew R Bennett; Liskin Swint-Kruse
Journal:  Proteins       Date:  2021-08-16

6.  Transcription activation by the siderophore sensor Btr is mediated by ligand-dependent stimulation of promoter clearance.

Authors:  Ahmed Gaballa; Shawn MacLellan; John D Helmann
Journal:  Nucleic Acids Res       Date:  2011-12-30       Impact factor: 16.971

7.  Backbone Interactions Between Transcriptional Activator ExsA and Anti-Activator ExsD Facilitate Regulation of the Type III Secretion System in Pseudomonas aeruginosa.

Authors:  Manisha Shrestha; Robert C Bernhards; Yichen Fu; Kylie Ryan; Florian D Schubot
Journal:  Sci Rep       Date:  2020-06-18       Impact factor: 4.379

8.  4-Chlorophenol Oxidation Depends on the Activation of an AraC-Type Transcriptional Regulator, CphR, in Rhodococcus sp. Strain YH-5B.

Authors:  Hui Zhang; Ting Yu; Yiran Wang; Jie Li; Guangli Wang; Yingqun Ma; Yu Liu
Journal:  Front Microbiol       Date:  2018-10-23       Impact factor: 5.640

9.  Quantifying the regulatory role of individual transcription factors in Escherichia coli.

Authors:  Sunil Guharajan; Shivani Chhabra; Vinuselvi Parisutham; Robert C Brewster
Journal:  Cell Rep       Date:  2021-11-09       Impact factor: 9.423
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.