Literature DB >> 11092841

The genetics of peroxisome biogenesis.

K A Sacksteder1, S J Gould.   

Abstract

The segregation of metabolic functions within discrete organelles is a hallmark of eukaryotic cells. These compartments allow for the concentration of related metabolic functions, the separation of competing metabolic functions, and the formation of unique chemical microenvironments. However, such organization is not spontaneous and requires an array of genes that are dedicated to the assembly and maintenance of these structures. In this review we focus on the genetics of peroxisome biogenesis and on how defects in this process cause human disease.

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Year:  2000        PMID： 11092841     DOI： 10.1146/annurev.genet.34.1.623

Source DB:  PubMed          Journal:  Annu Rev Genet        ISSN： 0066-4197            Impact factor:   16.830


  28 in total

1.  Functional studies on human Pex7p: subcellular localization and interaction with proteins containing a peroxisome-targeting signal type 2 and other peroxins.

Authors:  Karen Ghys; Marc Fransen; Guy P Mannaerts; Paul P Van Veldhoven
Journal:  Biochem J       Date:  2002-07-01       Impact factor: 3.857

2.  Interactions of Pex7p and Pex18p/Pex21p with the peroxisomal docking machinery: implications for the first steps in PTS2 protein import.

Authors:  Katharina Stein; Annette Schell-Steven; Ralf Erdmann; Hanspeter Rottensteiner
Journal:  Mol Cell Biol       Date:  2002-09       Impact factor: 4.272

3.  PEX5 protein binds monomeric catalase blocking its tetramerization and releases it upon binding the N-terminal domain of PEX14.

Authors:  Marta O Freitas; Tânia Francisco; Tony A Rodrigues; Inês S Alencastre; Manuel P Pinto; Cláudia P Grou; Andreia F Carvalho; Marc Fransen; Clara Sá-Miranda; Jorge E Azevedo
Journal:  J Biol Chem       Date:  2011-10-05       Impact factor: 5.157

4.  Two independent pathways traffic the intraperoxisomal peroxin PpPex8p into peroxisomes: mechanism and evolutionary implications.

Authors:  Lan Zhang; Sébastien Léon; Suresh Subramani
Journal:  Mol Biol Cell       Date:  2005-11-30       Impact factor: 4.138

5.  Characterization of the targeting signal of the Arabidopsis 22-kD integral peroxisomal membrane protein.

Authors:  Mary A Murphy; Belinda A Phillipson; Alison Baker; Robert T Mullen
Journal:  Plant Physiol       Date:  2003-09-04       Impact factor: 8.340

Review 6.  The Principles of Protein Targeting and Transport Across Cell Membranes.

Authors:  Yuanyuan Chen; Sri Karthika Shanmugam; Ross E Dalbey
Journal:  Protein J       Date:  2019-06       Impact factor: 2.371

7.  PEX11alpha is required for peroxisome proliferation in response to 4-phenylbutyrate but is dispensable for peroxisome proliferator-activated receptor alpha-mediated peroxisome proliferation.

Authors:  Xiaoling Li; Eveline Baumgart; Gao-Xiang Dong; James C Morrell; Gerardo Jimenez-Sanchez; David Valle; Kirby D Smith; Stephen J Gould
Journal:  Mol Cell Biol       Date:  2002-12       Impact factor: 4.272

Review 8.  The role of the endoplasmic reticulum in peroxisome biogenesis.

Authors:  Lazar Dimitrov; Sheung Kwan Lam; Randy Schekman
Journal:  Cold Spring Harb Perspect Biol       Date:  2013-05-01       Impact factor: 10.005

9.  Cryptococcus neoformans gene expression during murine macrophage infection.

Authors:  Weihua Fan; Peter R Kraus; Marie-Josee Boily; Joseph Heitman
Journal:  Eukaryot Cell       Date:  2005-08

10.  Inactivation of the endoplasmic reticulum protein translocation factor, Sec61p, or its homolog, Ssh1p, does not affect peroxisome biogenesis.

Authors:  S T South; E Baumgart; S J Gould
Journal:  Proc Natl Acad Sci U S A       Date:  2001-10-02       Impact factor: 11.205
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