Literature DB >> 1109265

Decontamination procedures for skin exposed to phenolic substances.

V K Brown, V L Box, B J Simpson.   

Abstract

Spraying or swabbing with a mixture of polyethylene glycol 300/industrial methylated spirits (PEG-300/IMS) (2:1 by volume) has been shown to substantially reduce mortality, systemic effects, and skin burns resulting from skin contamination by phenol, cumene hydroperoxide, or phenol/acetone cleavage product. The skin-damaging potentials of sodium hydroxide and sulfuric acid have also been investigated. PEG-300/IMS(2:1 by volume) mixture was found, in rats, to be slightly less effective than water as means of decontamination. The PEG-300/IMS mixture has been shown not to cause eye irritation, and so should not present a hazard where this mixture is used as a decontaminant spray.

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Year:  1975        PMID: 1109265     DOI: 10.1080/00039896.1975.10666623

Source DB:  PubMed          Journal:  Arch Environ Health        ISSN: 0003-9896


  3 in total

1.  Dermal Exposure to Cumene Hydroperoxide: Assessing Its Toxic Relevance and Oxidant Potential.

Authors:  Cynthia V Rider; Po Chan; Ron A Herbert; Grace E Kissling; Laurene M Fomby; Milton R Hejtmancik; Kristine L Witt; Suramya Waidyanatha; Greg S Travlos; Maria B Kadiiska
Journal:  Toxicol Pathol       Date:  2016-03-16       Impact factor: 1.902

2.  Phenol Toxicity Following Cutaneous Exposure to Creolin®: A Case Report.

Authors:  David Vearrier; Dorian Jacobs; Michael I Greenberg
Journal:  J Med Toxicol       Date:  2015-06

3.  Cecropia pachystachya: a species with expressive in vivo topical anti-inflammatory and in vitro antioxidant effects.

Authors:  Natália Ramos Pacheco; Nícolas de Castro Campos Pinto; Josiane Mello da Silva; Renata de Freitas Mendes; Juliana de Carvalho da Costa; Danielle Maria de Oliveira Aragão; Maria Christina Marques Nogueira Castañon; Elita Scio
Journal:  Biomed Res Int       Date:  2014-04-30       Impact factor: 3.411

  3 in total

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