Literature DB >> 11092473

Experimental acute intracerebral hemorrhage. Value of MR sequences for a safe diagnosis at 1.5 and 0.5 T.

W Küker1, R Thiex, I Rohde, V Rohde, A Thron.   

Abstract

PURPOSE: To determine the detectability of intracerebral hematomas with MR imaging at 1.5 T and 0.5 T with fluid attenuated inversion recovery turbo spinecho (FLAIR) and gradient-echo sequences.
MATERIAL AND METHODS: Twenty-seven intracerebral hematomas were created in 25 piglets by injection of venous blood into the brain through a burr hole. All were imaged with T2*-weighted gradient echo sequences (fast field echo, FFE), T2-weighted fluid attenuated inversion recovery turbo spin-echo sequences (FLAIR), T2-weighted turbo spin-echo (TSE) and T1-weighted spinecho sequences. Follow-up was performed on the 2nd, 4th and 10th postoperative days. Ten animals were additionally investigated with similar sequences at 0.5 T. Histologic correlation was obtained in all cases.
RESULTS: T2* FFE sequences detected all acute intracerebral hematomas and demonstrated the size correctly at 1.5 T and 0.5 T. The conspicuity was better at 1.5 T. FLAIR sequences were unreliable in the hyperacute phase at 1.5 T: However. subarachnoid and intraventricular extension was best appreciated with FLAIR images. T2 TSE images were incapable of detecting paraventricular and subarachnoid hemorrhages, but clearly demonstrated intracerebral blood in other locations. TI-weighted images were insensitive to hemorrhage in the acute state but very useful in subacute and chronic hematomas.
CONCLUSION: The safe and reliable diagnosis of intracerebral hemorrhage is probably possible with MR imaging at 1.5 T and 0.5 T even of hematomas less than 90 min old, but requires the application of at least FLAIR, T2* FFE and T1 sequences and is therefore time consuming.

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Year:  2000        PMID: 11092473     DOI: 10.1080/028418500127346180

Source DB:  PubMed          Journal:  Acta Radiol        ISSN: 0284-1851            Impact factor:   1.701


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