Literature DB >> 11091541

Significance of Flow Cytometric DNA Analysis from Freshly Aspirated Samples.

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Abstract

The procedure of aspiration biopsy cytology by fine needle aspiration (ABC) is as option in establishing definitive diagnoses for breast cancers. In this series, a needle size of 21G was considered most suitable for ABC as well as flow cytometric DNA analysis. Histograms from fresh samples aspirated by fine needle clearly delineated a sharp peak in G&sup0;G(1) phases and also a better CV was obtained than with paraffin-embedded preparations. In addition, fresh samples gave more reliable DI and suggested the value of measuring nuclear DNA contents. It is believed that the prognoses of breast cancers are closely associated with DNA ploidy patterns. In this sense, flow cytometric DNA analysis of fresh samples of ABC is regarded as important in clinical use.

Entities:  

Year:  1995        PMID： 11091541     DOI： 10.1007/BF02966949

Source DB:  PubMed          Journal:  Breast Cancer        ISSN： 1340-6868            Impact factor:   4.239


  16 in total

1.  Emerging impact of flow cytometry in predicting recurrence and survival in breast cancer patients.

Authors:  W L McGuire; L G Dressler
Journal:  J Natl Cancer Inst       Date:  1985-09       Impact factor: 13.506

2.  Loss of heterozygosity on the short arm of chromosome 17 is associated with high proliferative capacity and DNA aneuploidy in primary human breast cancer.

Authors:  L C Chen; A Neubauer; W Kurisu; F M Waldman; B M Ljung; W Goodson; E S Goldman; D Moore; M Balazs; E Liu
Journal:  Proc Natl Acad Sci U S A       Date:  1991-05-01       Impact factor: 11.205

3.  DNA index and S-phase fraction and their combination as prognostic factors in operable ductal breast carcinoma.

Authors:  H Joensuu; S Toikkanen; P J Klemi
Journal:  Cancer       Date:  1990-07-15       Impact factor: 6.860

4.  Immunodetection of the metastasis-associated laminin receptor in human breast cancer cells obtained by fine-needle aspiration biopsy.

Authors:  V Castronovo; C Colin; A P Claysmith; P H Chen; E Lifrange; R Lambotte; H Krutzsch; L A Liotta; M E Sobel
Journal:  Am J Pathol       Date:  1990-12       Impact factor: 4.307

5.  The value of aspiration cytology in the diagnosis of breast cancer: experience at the Fondation Curie.

Authors:  A Zajdela; N A Ghossein; J P Pilleron; A Ennuyer
Journal:  Cancer       Date:  1975-02       Impact factor: 6.860

6.  Stage II breast cancer is not simply a late stage I.

Authors:  C B Mueller
Journal:  Surgery       Date:  1988-10       Impact factor: 3.982

7.  Fine-needle aspiration of breast cancer. Relationship of clinical factors to cytology results in 689 primary malignancies.

Authors:  G H Barrows; T J Anderson; J L Lamb; J M Dixon
Journal:  Cancer       Date:  1986-10-01       Impact factor: 6.860

8.  Influence of cellular DNA content on disease-free survival of Stage II breast cancer patients.

Authors:  D W Hedley; C A Rugg; A B Ng; I W Taylor
Journal:  Cancer Res       Date:  1984-11       Impact factor: 12.701

9.  DNA ploidy and survival in breast cancer patients.

Authors:  C J Cornelisse; C J van de Velde; R J Caspers; A J Moolenaar; J Hermans
Journal:  Cytometry       Date:  1987-03

10.  Relationship of steroid receptor, cell kinetics, and clinical status in patients with breast cancer.

Authors:  T E Kute; H B Muss; D Anderson; K Crumb; B Miller; D Burns; L A Dube
Journal:  Cancer Res       Date:  1981-09       Impact factor: 12.701
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