| Literature DB >> 11089864 |
J Joubès1, C Chevalier, D Dudits, E Heberle-Bors, D Inzé, M Umeda, J P Renaudin.
Abstract
Cyclin-dependent kinases (CDK) form a conserved superfamily of eukaryotic serine-threonine protein kinases, which require binding to a cyclin protein for activity. CDK are involved in different aspects of cell biology and notably in cell cycle regulation. The comparison of nearly 50 plant CDK-related cDNAs with a selected set of their animal and yeast counterparts reveals five classes of these genes in plants. These are described here with respect to their phylogenetic, structural and functional properties. A plant-wide nomenclature of CDK-related genes is proposed, using a system similar to that of the plant cyclin genes. The most numerous class, CDKA, includes genes coding for CDK with the PSTAIRE canonical motif. CDKB makes up a class of plant-specific CDK divided into two groups: CDKB1 and CDKB2. CDKC, CDKD and CDKE form less numerous classes. The CDKD class includes the plant orthologues of metazoan CDK7, which correspond to the CDK-activating kinase (CAK). At present, no functional information is available in plants for CDKC and CDKE.Entities:
Mesh：
Substances：
Year: 2000 PMID： 11089864 DOI： 10.1023/a:1006470301554
Source DB: PubMed Journal: Plant Mol Biol ISSN： 0167-4412 Impact factor: 4.076