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22 in total

1. Trapped topoisomerase II initiates formation of de novo duplications via the nonhomologous end-joining pathway in yeast.

Authors: Nicole Stantial; Anna Rogojina; Matthew Gilbertson; Yilun Sun; Hannah Miles; Samantha Shaltz; James Berger; Karin C Nitiss; Sue Jinks-Robertson; John L Nitiss
Journal: Proc Natl Acad Sci U S A Date: 2020-10-12 Impact factor: 11.205

2. SCAN1 mutant Tdp1 accumulates the enzyme--DNA intermediate and causes camptothecin hypersensitivity.

Authors: Heidrun Interthal; Hong Jing Chen; Thomas E Kehl-Fie; Jörg Zotzmann; John B Leppard; James J Champoux
Journal: EMBO J Date: 2005-05-26 Impact factor: 11.598

3. The anticancer thiosemicarbazones Dp44mT and triapine lack inhibitory effects as catalytic inhibitors or poisons of DNA topoisomerase IIα.

Authors: Jack C Yalowich; Xing Wu; Rui Zhang; Ragu Kanagasabai; Marisa Hornbaker; Brian B Hasinoff
Journal: Biochem Pharmacol Date: 2012-04-04 Impact factor: 5.858

4. Phosphorylation of BLM, dissociation from topoisomerase IIIalpha, and colocalization with gamma-H2AX after topoisomerase I-induced replication damage.

Authors: V Ashutosh Rao; Angela M Fan; Linghua Meng; Christopher F Doe; Phillip S North; Ian D Hickson; Yves Pommier
Journal: Mol Cell Biol Date: 2005-10 Impact factor: 4.272

5. Endogenous assays of DNA methyltransferases: Evidence for differential activities of DNMT1, DNMT2, and DNMT3 in mammalian cells in vivo.

Authors: Kui Liu; Yun Fei Wang; Carmen Cantemir; Mark T Muller
Journal: Mol Cell Biol Date: 2003-04 Impact factor: 4.272

ICE bioassay. Isolating in vivo complexes of enzyme to DNA.

1. Trapped topoisomerase II initiates formation of de novo duplications via the nonhomologous end-joining pathway in yeast.

2. SCAN1 mutant Tdp1 accumulates the enzyme--DNA intermediate and causes camptothecin hypersensitivity.

3. The anticancer thiosemicarbazones Dp44mT and triapine lack inhibitory effects as catalytic inhibitors or poisons of DNA topoisomerase IIα.

4. Phosphorylation of BLM, dissociation from topoisomerase IIIalpha, and colocalization with gamma-H2AX after topoisomerase I-induced replication damage.

5. Endogenous assays of DNA methyltransferases: Evidence for differential activities of DNMT1, DNMT2, and DNMT3 in mammalian cells in vivo.

6. Transcription-dependent degradation of topoisomerase I-DNA covalent complexes.

Review 7. Iron chelators with topoisomerase-inhibitory activity and their anticancer applications.

8. The anticancer multi-kinase inhibitor dovitinib also targets topoisomerase I and topoisomerase II.

9. Repair of DNA damage induced by the mycotoxin alternariol involves tyrosyl-DNA phosphodiesterase 1.

10. Isolation and quantitation of topoisomerase complexes accumulated on Escherichia coli chromosomal DNA.