Successful use of combination chemotherapy in pure red cell aplasia associated with malignant lymphoma, histiocytic type.

A case of pure red cell aplasia developing in a woman aged 78 is reported. Biopsy of an enlarged axillary lymph node disclosed a malignant lymphoma, histiocytic type. Therapy with intermittent cyclophosphamide and prednisone was instituted. There was rapid remission of the red cell aplasia. Clinical recurrence of the histiocytic lymphoma has not occurred.