Literature DB >> 11087558

Biarylpropylsulfonamides as novel, potent potentiators of 2-amino-3- (5-methyl-3-hydroxyisoxazol-4-yl)- propanoic acid (AMPA) receptors.

P L Ornstein1, D M Zimmerman, M B Arnold, T J Bleisch, B Cantrell, R Simon, H Zarrinmayeh, S R Baker, M Gates, J P Tizzano, D Bleakman, A Mandelzys, K R Jarvie, K Ho, M Deverill, R K Kamboj.   

Abstract

Entities:  

Mesh：

Substances：

Year:  2000        PMID： 11087558     DOI： 10.1021/jm0002836

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


× No keyword cloud information.
  7 in total

1.  Combinatorial chemistry and high-throughput screening in drug discovery: different strategies and formats.

Authors:  P Seneci; S Miertus
Journal:  Mol Divers       Date:  2000       Impact factor: 2.943

Review 2.  Challenges for and current status of research into positive modulators of AMPA receptors.

Authors:  Simon E Ward; Benjamin D Bax; Mark Harries
Journal:  Br J Pharmacol       Date:  2010-05       Impact factor: 8.739

Review 3.  Therapeutic potential of positive AMPA receptor modulators in the treatment of neuropsychiatric disorders.

Authors:  Stefano Marenco; Daniel R Weinberger
Journal:  CNS Drugs       Date:  2006       Impact factor: 5.749

4.  Rational Design of a Novel AMPA Receptor Modulator through a Hybridization Approach.

Authors:  Nicola Caldwell; Jonathan E Harms; Kathryn M Partin; Craig Jamieson
Journal:  ACS Med Chem Lett       Date:  2015-02-11       Impact factor: 4.345

5.  Molecular mechanism of flop selectivity and subsite recognition for an AMPA receptor allosteric modulator: structures of GluA2 and GluA3 in complexes with PEPA.

Authors:  Ahmed H Ahmed; Christopher P Ptak; Robert E Oswald
Journal:  Biochemistry       Date:  2010-04-06       Impact factor: 3.162

6.  Structural and functional analysis of two new positive allosteric modulators of GluA2 desensitization and deactivation.

Authors:  David E Timm; Morris Benveniste; Autumn M Weeks; Eric S Nisenbaum; Kathryn M Partin
Journal:  Mol Pharmacol       Date:  2011-05-04       Impact factor: 4.436

Review 7.  Positive AMPA receptor modulation in the treatment of neuropsychiatric disorders: A long and winding road.

Authors:  Bashkim Kadriu; Laura Musazzi; Jenessa N Johnston; Lisa E Kalynchuk; Hector J Caruncho; Maurizio Popoli; Carlos A Zarate
Journal:  Drug Discov Today       Date:  2021-08-03       Impact factor: 8.369
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.