Literature DB >> 11086922

Isolation of a potent anti-MRSA sesquiterpenoid quinone from Ulmus davidiana var. japonica.

D Y Shin1, H S Kim, K H Min, S S Hyun, S A Kim, H Huh, E C Choi, Y H Choi, J Kim, S H Choi, W B Kim, Y G Suh.   

Abstract

A highly potent anti-MRSA sesquiterpenoid has been isolated from Ulmus davidiana var. japonica, which has been traditionally used to treat infectious diseases in Korea. This naturally occurring antibiotic was identified as mansonone F (1). This compound has been found to be highly active specifically against MRSA and showed an MIC range of 0.39-3.13 microg/ml which is comparable to that of vancomycin.

Entities:  

Mesh:

Substances:

Year:  2000        PMID: 11086922     DOI: 10.1248/cpb.48.1805

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN: 0009-2363            Impact factor:   1.645


  4 in total

1.  Regulation of Cytokines and Dihydrotestosterone Production in Human Hair Follicle Papilla Cells by Supercritical Extraction-Residues Extract of Ulmus davidiana.

Authors:  Ye-Eun Kwon; Sun-Eun Choi; Kwang-Hyun Park
Journal:  Molecules       Date:  2022-02-19       Impact factor: 4.411

2.  Vasorelaxing Activity of Ulmus davidiana Ethanol Extracts in Rats: Activation of Endothelial Nitric Oxide Synthase.

Authors:  Eun Jung Cho; Myoung Soo Park; Sahng Seop Kim; Gun Kang; Sunga Choi; Yoo Rhan Lee; Seok Jong Chang; Kwon Ho Lee; Sang Do Lee; Jin Bong Park; Byeong Hwa Jeon
Journal:  Korean J Physiol Pharmacol       Date:  2011-12-27       Impact factor: 2.016

Review 3.  Antibiotics and bioactive natural products in treatment of methicillin resistant Staphylococcus aureus: A brief review.

Authors:  Arunava Kali
Journal:  Pharmacogn Rev       Date:  2015 Jan-Jun

4.  Ulmus davidiana ethanol extract inhibits monocyte adhesion to tumor necrosis factor-alpha-stimulated endothelial cells.

Authors:  Ki Mo Lee; Hee Kyoung Joo; Yu Ran Lee; Myoung Soo Park; Gun Kang; Sunga Choi; Kwon Ho Lee; Byeong Hwa Jeon
Journal:  Integr Med Res       Date:  2016-03-31
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.