| Literature DB >> 11086720 |
N Murakami1, M Sugimoto, M Morita, S Akiyama, M Kobayashi.
Abstract
4-Deacetoxyagosterol A was synthesized from ergosterol by utilizing reductive regioselective epoxy cleavage as a key reaction. This synthesized congener of agosterol A, a spongean MDR-modulator. showed similar MDR-modulating activity against KB CV-60 cells overexpressing MRP.Entities:
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Year: 2000 PMID： 11086720 DOI： 10.1016/s0960-894x(00)00502-3
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823