| Literature DB >> 11086183 |
F Girodon1, P M Carli, B Favre, L Mannone, S Houssaye, F Mugneret, O Casasnovas, M Maynadié.
Abstract
We report here the case of a woman with acute myeloid leukemia with some blast cells exhibiting acute promyelocytic leukemia (APL)-like hypergranular cytoplasm. The cytologic and cytochemical aspects as well as the mature myeloid phenotype and hemostasis disorders were consistent with the diagnosis of APL. However, no t(15;17), or RARalpha gene, MLL gene or PML gene rearrangement was observed, or any other cytogenetic clonal abnormality. Coexpression on blast cells of CD33 and CD56 without CD34, CD16 or HLA-DR, suggested a myeloid/natural killer cell acute leukemia.Entities:
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Year: 2000 PMID： 11086183 DOI： 10.1016/s0145-2126(00)00068-0
Source DB: PubMed Journal: Leuk Res ISSN： 0145-2126 Impact factor: 3.156