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Literature DB >> 11085767

Leukotriene receptor antagonist therapy.

Abstract

Leukotriene receptor antagonists (LTRA) are a new class of drugs for asthma treatment, available in tablet form. Their unique mechanism of action results in a combination of both bronchodilator and anti-inflammatory effects. While their optimal place in asthma management is still under review, LTRA represent an important advance in asthma pharmacotherapy.

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Year: 2000 PMID： 11085767 PMCID： PMC1741850 DOI： 10.1136/pmj.76.902.767

Source DB: PubMed Journal: Postgrad Med J ISSN： 0032-5473 Impact factor: 2.401

54 in total

1. Prevention of severe premenstrual asthma attacks by leukotriene receptor antagonist.

Authors: H Nakasato; T Ohrui; K Sekizawa; T Matsui; M Yamaya; G Tamura; H Sasaki
Journal: J Allergy Clin Immunol Date: 1999-09 Impact factor: 10.793

2. Montelukast for chronic asthma in 6- to 14-year-old children: a randomized, double-blind trial. Pediatric Montelukast Study Group.

Authors: B Knorr; J Matz; J A Bernstein; H Nguyen; B C Seidenberg; T F Reiss; A Becker
Journal: JAMA Date: 1998-04-15 Impact factor: 56.272

3. Montelukast once daily inhibits exercise-induced bronchoconstriction in 6- to 14-year-old children with asthma.

Authors: J P Kemp; R J Dockhorn; G G Shapiro; H H Nguyen; T F Reiss; B C Seidenberg; B Knorr
Journal: J Pediatr Date: 1998-09 Impact factor: 4.406

4. Naturally occurring mutations in the human 5-lipoxygenase gene promoter that modify transcription factor binding and reporter gene transcription.

Authors: K H In; K Asano; D Beier; J Grobholz; P W Finn; E K Silverman; E S Silverman; T Collins; A R Fischer; T P Keith; K Serino; S W Kim; G T De Sanctis; C Yandava; A Pillari; P Rubin; J Kemp; E Israel; W Busse; D Ledford; J J Murray; A Segal; D Tinkleman; J M Drazen
Journal: J Clin Invest Date: 1997-03-01 Impact factor: 14.808

5. Dose-related protection of exercise bronchoconstriction by montelukast, a cysteinyl leukotriene-receptor antagonist, at the end of a once-daily dosing interval.

Authors: E A Bronsky; J P Kemp; J Zhang; D Guerreiro; T F Reiss
Journal: Clin Pharmacol Ther Date: 1997-11 Impact factor: 6.875

6. Identification, molecular cloning, expression, and characterization of a cysteinyl leukotriene receptor.

Authors: H M Sarau; R S Ames; J Chambers; C Ellis; N Elshourbagy; J J Foley; D B Schmidt; R M Muccitelli; O Jenkins; P R Murdock; N C Herrity; W Halsey; G Sathe; A I Muir; P Nuthulaganti; G M Dytko; P T Buckley; S Wilson; D J Bergsma; D W Hay
Journal: Mol Pharmacol Date: 1999-09 Impact factor: 4.436

7. Therapeutic effect of zafirlukast as monotherapy in steroid-naive patients with severe persistent asthma.

Authors: J P Kemp; M C Minkwitz; C M Bonuccelli; M S Warren
Journal: Chest Date: 1999-02 Impact factor: 9.410

8. Leukotrienes and inflammation

Authors:
Journal: Am J Respir Crit Care Med Date: 1998-06 Impact factor: 21.405

9. Zafirlukast improves asthma symptoms and quality of life in patients with moderate reversible airflow obstruction.

Authors: R A Nathan; J A Bernstein; L Bielory; C M Bonuccelli; W J Calhoun; S P Galant; L A Hanby; J P Kemp; J W Kylstra; A S Nayak; J P O'Connor; H J Schwartz; D L Southern; S L Spector; P V Williams
Journal: J Allergy Clin Immunol Date: 1998-12 Impact factor: 10.793

10. Effect of oral prednisone on airway inflammatory mediators in atopic asthma.

Authors: R Dworski; G A Fitzgerald; J A Oates; J R Sheller
Journal: Am J Respir Crit Care Med Date: 1994-04 Impact factor: 21.405

6 in total

Review 1. Role of leukotriene receptor antagonists in the management of pediatric asthma: an update.

Authors: Catalina Dumitru; Susan M H Chan; Victor Turcanu
Journal: Paediatr Drugs Date: 2012-10-01 Impact factor: 3.022

Review 2. Crosstalk Between Signaling Pathways Involved in the Regulation of Airway Smooth Muscle Cell Hyperplasia.

Authors: Hui Min Yap; Daud Ahmad Israf; Hanis Hazeera Harith; Chau Ling Tham; Mohd Roslan Sulaiman
Journal: Front Pharmacol Date: 2019-10-09 Impact factor: 5.810

3. ADRB2 haplotypes and asthma exacerbations in children and young adults: An individual participant data meta-analysis.

Authors: Leila Karimi; Susanne J Vijverberg; Marjolein Engelkes; Natalia Hernandez-Pacheco; Niloufar Farzan; Patricia Soares; Maria Pino-Yanes; Andrea L Jorgensen; Celeste Eng; Somnath Mukhopadhyay; Maximilian Schieck; Michael Kabesch; Esteban G Burchard; Fook Tim Chew; Yang Yie Sio; Uroš Potočnik; Mario Gorenjak; Daniel B Hawcutt; Colin N Palmer; Steve Turner; Hettie M Janssens; Anke H Maitland-van der Zee; Katia M C Verhamme
Journal: Clin Exp Allergy Date: 2021-07-20 Impact factor: 5.401