Literature DB >> 11084403

[Malignant or necrotizing otitis externa: experience in 22 cases].

J Martel1, J Y Duclos, V Darrouzet, M Guyot, J P Bébéar.   

Abstract

Malignant or progressive necrotizing otitis extrema is an uncommon but severe infectious condition of the external auditory canal. Over a period of four years, we treated 22 patients: 60% had diabetes (1/4 insulin dependent) and 13% were immunodepressed. The causal germ was Pseudomonas aeruginosa in 87% of cases. The pretherapeutic work-up included a computed tomography scan and a technetium scintigraphy to confirm diagnosis and assess extension. Repeated scintigraphies with gallium were used to follow the course under treatment. Medical treatment was used in most cases (16/22) with parenteral antibiotic therapy using a third-generation cephalosporin (ceftazidime or ceftriaxone) and a fluoroquinolone (ciprofloxacin or ofloxacin) and, if there was no contraindication, hyperbaric oxygen. Surgery is not indicated in malignant otitis externa. We had a 95% cure rate with only 10% recurrence. We reviewed the data in the literature on malignant otitis externa and present the important diagnostic, imaging and therapeutic aspects.

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Year:  2000        PMID: 11084403

Source DB:  PubMed          Journal:  Ann Otolaryngol Chir Cervicofac        ISSN: 0003-438X


  4 in total

1.  Adjunctive hyperbaric oxygen in pseudomonas keratitis.

Authors:  Robert Chong; Chandra J Ayer; Ian C Francis; Minas T Coroneo; Darren L Wolfers
Journal:  Br J Ophthalmol       Date:  2007-04       Impact factor: 4.638

Review 2.  Antibiotic therapy in necrotising external otitis: case series of 32 patients and review of the literature.

Authors:  C Pulcini; P Mahdyoun; E Cua; I Gahide; L Castillo; N Guevara
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2012-07-19       Impact factor: 3.267

3.  Additive value of 99mTechnetium methylene diphosphonate hybrid single-photon emission computed tomography/computed tomography in the diagnosis of skull base osteomyelitis in otitis externa patients compared to planar bone scintigraphy.

Authors:  Jehan Ahmed Younis
Journal:  World J Nucl Med       Date:  2018 Oct-Dec

4.  Skull base osteomyelitis in otitis externa: The utility of triphasic and single photon emission computed tomography/computed tomography bone scintigraphy.

Authors:  Dhritiman Chakraborty; Anish Bhattacharya; Ashok Kumar Gupta; Naresh Kumar Panda; Ashim Das; Bhagwant Rai Mittal
Journal:  Indian J Nucl Med       Date:  2013-04
  4 in total

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