| Literature DB >> 11084354 |
M Lieber1.
Abstract
Recent work indicates that mutations in a cytidine deaminase homologue ablate both immunoglobulin class switch recombination and somatic hypermutation. These findings now explain cases of autosomal hyper-IgM syndrome and reveal that critical components for key functions of B cells require RNA editing.Entities:
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Year: 2000 PMID： 11084354 DOI： 10.1016/s0960-9822(00)00766-1
Source DB: PubMed Journal: Curr Biol ISSN： 0960-9822 Impact factor: 10.834