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Literature DB >> 11084353

Muscular dystrophy: the worm turns to genetic disease.

Abstract

A new animal model for studying muscular dystrophy, a mutant form of the nematode Caenorhabditis elegans, brings the power of worm genetics to bear on the search for a cure for this disease; work on this worm has already led to the identification of a novel component that can suppress the mutant phenotype.

Entities: Disease Species

Mesh：

Substances：
Dystrophin

Year: 2000 PMID： 11084353 DOI： 10.1016/s0960-9822(00)00768-5

Source DB: PubMed Journal: Curr Biol ISSN： 0960-9822 Impact factor: 10.834

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Cited

17 in total

1. Learning cell biology as a team: a project-based approach to upper-division cell biology.

Authors: Robin Wright; James Boggs
Journal: Cell Biol Educ Date: 2002

Review 2. Duchenne's muscular dystrophy: animal models used to investigate pathogenesis and develop therapeutic strategies.

Authors: C A Collins; J E Morgan
Journal: Int J Exp Pathol Date: 2003-08 Impact factor: 1.925

3. Multi-environment model estimation for motility analysis of Caenorhabditis elegans.

Authors: Raphael Sznitman; Manaswi Gupta; Gregory D Hager; Paulo E Arratia; Josué Sznitman
Journal: PLoS One Date: 2010-07-22 Impact factor: 3.240

4. Loss of dystrophin and the microtubule-binding protein ELP-1 causes progressive paralysis and death of adult C. elegans.

Authors: Jennifer L Hueston; Kathy A Suprenant
Journal: Dev Dyn Date: 2009-08 Impact factor: 3.780

Review 5. Absence of Dystrophin Disrupts Skeletal Muscle Signaling: Roles of Ca2+, Reactive Oxygen Species, and Nitric Oxide in the Development of Muscular Dystrophy.

Authors: David G Allen; Nicholas P Whitehead; Stanley C Froehner
Journal: Physiol Rev Date: 2016-01 Impact factor: 37.312

10. A decline in transcript abundance for Heterodera glycines homologs of Caenorhabditis elegans uncoordinated genes accompanies its sedentary parasitic phase.

Authors: Vincent P Klink; Veronica E Martins; Nadim W Alkharouf; Christopher C Overall; Margaret H MacDonald; Benjamin F Matthews
Journal: BMC Dev Biol Date: 2007-04-19 Impact factor: 1.978

Muscular dystrophy: the worm turns to genetic disease.

1. Learning cell biology as a team: a project-based approach to upper-division cell biology.

Review 2. Duchenne's muscular dystrophy: animal models used to investigate pathogenesis and develop therapeutic strategies.

3. Multi-environment model estimation for motility analysis of Caenorhabditis elegans.

4. Loss of dystrophin and the microtubule-binding protein ELP-1 causes progressive paralysis and death of adult C. elegans.

Review 5. Absence of Dystrophin Disrupts Skeletal Muscle Signaling: Roles of Ca2+, Reactive Oxygen Species, and Nitric Oxide in the Development of Muscular Dystrophy.

6. NemaFlex: a microfluidics-based technology for standardized measurement of muscular strength of C. elegans.

7. Studying human disease genes in Caenorhabditis elegans: a molecular genetics laboratory project.

Review 8. Caenorhabditis elegans as a Model System for Duchenne Muscular Dystrophy.

9. Identification of potential therapeutic drugs for huntington's disease using Caenorhabditis elegans.

10. A decline in transcript abundance for Heterodera glycines homologs of Caenorhabditis elegans uncoordinated genes accompanies its sedentary parasitic phase.