Literature DB >> 11083841

DNA rearrangements in the flagellin locus of an flaA mutant of Campylobacter jejuni during colonization of chicken ceca.

P J Nuijten1, A J van den Berg, I Formentini, B A van der Zeijst, A A Jacobs.   

Abstract

Campylobacter jejuni is an enteropathogen for humans but commensal for chickens. In both hosts, the flagella and motility are important colonization factors. The flagellin gene is duplicated in Campylobacter, but only one flagellin gene, flaA, is sufficient for motility. We found that, during colonization of the chicken intestine, a nonmotile flaA mutant of C. jejuni underwent rearrangements within its flagellin locus, thereby regaining its motility and colonization capacity. In contrast, in vitro motile revertants isolated from liquid culture showed different flagellin DNA rearrangements than after reversion in the chicken.

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Year:  2000        PMID： 11083841      PMCID： PMC97826          DOI： 10.1128/IAI.68.12.7137-7140.2000

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  14 in total

1.  Genomic organization and expression of Campylobacter flagellin genes.

Authors:  P Guerry; S M Logan; S Thornton; T J Trust
Journal:  J Bacteriol       Date:  1990-04       Impact factor: 3.490

Review 2.  Bacterial antigenic variation, host immune response, and pathogen-host coevolution.

Authors:  R C Brunham; F A Plummer; R S Stephens
Journal:  Infect Immun       Date:  1993-06       Impact factor: 3.441

3.  Structural and functional analysis of two Campylobacter jejuni flagellin genes.

Authors:  P J Nuijten; F J van Asten; W Gaastra; B A van der Zeijst
Journal:  J Biol Chem       Date:  1990-10-15       Impact factor: 5.157

4.  Genomic rearrangements in the flagellin genes of Proteus mirabilis.

Authors:  C A Murphy; R Belas
Journal:  Mol Microbiol       Date:  1999-01       Impact factor: 3.501

5.  A sister-strand exchange mechanism for recA-independent deletion of repeated DNA sequences in Escherichia coli.

Authors:  S T Lovett; P T Drapkin; V A Sutera; T J Gluckman-Peskind
Journal:  Genetics       Date:  1993-11       Impact factor: 4.562

6.  Significance of duplicated flagellin genes in Campylobacter.

Authors:  R A Alm; P Guerry; T J Trust
Journal:  J Mol Biol       Date:  1993-03-20       Impact factor: 5.469

7.  Differential flagellin expression in a flaA flaB+ mutant of Campylobacter jejuni.

Authors:  T M Wassenaar; N M Bleumink-Pluym; D G Newell; P J Nuijten; B A van der Zeijst
Journal:  Infect Immun       Date:  1994-09       Impact factor: 3.441

8.  Role of Campylobacter jejuni flagella as colonization factors for three-day-old chicks: analysis with flagellar mutants.

Authors:  I Nachamkin; X H Yang; N J Stern
Journal:  Appl Environ Microbiol       Date:  1993-05       Impact factor: 4.792

9.  Isotype, specificity, and kinetics of systemic and mucosal antibodies to Campylobacter jejuni antigens, including flagellin, during experimental oral infections of chickens.

Authors:  S Cawthraw; R Ayling; P Nuijten; T Wassenaar; D G Newell
Journal:  Avian Dis       Date:  1994 Apr-Jun       Impact factor: 1.577

10.  Inactivation of Campylobacter jejuni flagellin genes by homologous recombination demonstrates that flaA but not flaB is required for invasion.

Authors:  T M Wassenaar; N M Bleumink-Pluym; B A van der Zeijst
Journal:  EMBO J       Date:  1991-08       Impact factor: 11.598
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  14 in total

1.  Functional analysis of the RdxA and RdxB nitroreductases of Campylobacter jejuni reveals that mutations in rdxA confer metronidazole resistance.

Authors:  Deborah A Ribardo; Lacey K Bingham-Ramos; David R Hendrixson
Journal:  J Bacteriol       Date:  2010-01-29       Impact factor: 3.490

2.  Cj0596 is a periplasmic peptidyl prolyl cis-trans isomerase involved in Campylobacter jejuni motility, invasion, and colonization.

Authors:  Kimberly M Rathbun; Johanna E Hall; Stuart A Thompson
Journal:  BMC Microbiol       Date:  2009-08-08       Impact factor: 3.605

3.  Gene expression profile of Campylobacter jejuni in response to growth temperature variation.

Authors:  Alain Stintzi
Journal:  J Bacteriol       Date:  2003-03       Impact factor: 3.490

4.  In vivo tracking of Campylobacter jejuni by using a novel recombinant expressing green fluorescent protein.

Authors:  Philip F Mixter; John D Klena; Gary A Flom; Amy M Siegesmund; Michael E Konkel
Journal:  Appl Environ Microbiol       Date:  2003-05       Impact factor: 4.792

5.  Multiplex strategy for multilocus sequence typing, fla typing, and genetic determination of antimicrobial resistance of Campylobacter jejuni and Campylobacter coli isolates collected in Switzerland.

Authors:  Bozena M Korczak; Monika Zurfluh; Stefan Emler; Jacqueline Kuhn-Oertli; Peter Kuhnert
Journal:  J Clin Microbiol       Date:  2009-05-13       Impact factor: 5.948

6.  Cj0011c, a periplasmic single- and double-stranded DNA-binding protein, contributes to natural transformation in Campylobacter jejuni.

Authors:  Byeonghwa Jeon; Qijing Zhang
Journal:  J Bacteriol       Date:  2007-08-10       Impact factor: 3.490

7.  Adaptation of Campylobacter jejuni NCTC11168 to high-level colonization of the avian gastrointestinal tract.

Authors:  Michael A Jones; Kerrie L Marston; Claire A Woodall; Duncan J Maskell; Dennis Linton; Andrey V Karlyshev; Nick Dorrell; Brendan W Wren; Paul A Barrow
Journal:  Infect Immun       Date:  2004-07       Impact factor: 3.441

8.  A framework for assessing the concordance of molecular typing methods and the true strain phylogeny of Campylobacter jejuni and C. coli using draft genome sequence data.

Authors:  Catherine D Carrillo; Peter Kruczkiewicz; Steven Mutschall; Andrei Tudor; Clifford Clark; Eduardo N Taboada
Journal:  Front Cell Infect Microbiol       Date:  2012-05-01       Impact factor: 5.293

9.  Natural transformation of Campylobacter jejuni occurs beyond limits of growth.

Authors:  Christina S Vegge; Lone Brøndsted; Małgorzata Ligowska-Marzęta; Hanne Ingmer
Journal:  PLoS One       Date:  2012-09-26       Impact factor: 3.240

10.  Genome dynamics of Campylobacter jejuni in response to bacteriophage predation.

Authors:  Andrew E Scott; Andrew R Timms; Phillippa L Connerton; Catherine Loc Carrillo; Khairul Adzfa Radzum; Ian F Connerton
Journal:  PLoS Pathog       Date:  2007-08-24       Impact factor: 6.823
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