Literature DB >> 1108203

Characterization of a cell-lethal product from the photooxidation of tryptophan: hydrogen peroxide.

J P McCormick, J R Fischer, J P Pachlatko, A Eisenstark.   

Abstract

Near-ultraviolet (300 to 400 nanometers) irradiation of saturated, oxygenated solutions of tryptophan in the absence of added sensitizer gives rise to substances that have various biological effects on isolated cells, including mutagenicity and selective lethality to recombination-deficient bacterial mutants. One of these biologically active products has been identified as H2O2, on the basis of spectrometric, chromatographic, chemical, and biological properties. Now H2O2 has been shown to account for the biological activities mentioned above.

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Year:  1976        PMID: 1108203     DOI: 10.1126/science.1108203

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  29 in total

Review 1.  A free-radical hypothesis for the instability and evolution of genotype and phenotype in vitro.

Authors:  R E Parchment; K Natarajan
Journal:  Cytotechnology       Date:  1992       Impact factor: 2.058

2.  The spectrum of mutations generated by passage of a hydrogen peroxide damaged shuttle vector plasmid through a mammalian host.

Authors:  E C Moraes; S M Keyse; M Pidoux; R M Tyrrell
Journal:  Nucleic Acids Res       Date:  1989-10-25       Impact factor: 16.971

3.  Bactericidal effect of anaerobic broth exposed to atmospheric oxygen tested on Peptostreptococcus anaerobius.

Authors:  F Frölander; J Carlsson
Journal:  J Clin Microbiol       Date:  1977-08       Impact factor: 5.948

4.  Toxicity of Irradiated Media for Xenorhabdus spp.

Authors:  J Xu; R E Hurlbert
Journal:  Appl Environ Microbiol       Date:  1990-03       Impact factor: 4.792

5.  Epidermal trans-urocanic acid and the UV-A-induced photoaging of the skin.

Authors:  K M Hanson; J D Simon
Journal:  Proc Natl Acad Sci U S A       Date:  1998-09-01       Impact factor: 11.205

6.  Exonuclease III and the catalase hydroperoxidase II in Escherichia coli are both regulated by the katF gene product.

Authors:  B D Sak; A Eisenstark; D Touati
Journal:  Proc Natl Acad Sci U S A       Date:  1989-05       Impact factor: 11.205

7.  Control of sensitivity to inactivation by H2O2 and broad-spectrum near-UV radiation by the Escherichia coli katF locus.

Authors:  L J Sammartano; R W Tuveson; R Davenport
Journal:  J Bacteriol       Date:  1986-10       Impact factor: 3.490

8.  Repair of hydrogen peroxide-induced single-strand breaks in Escherichia coli deoxyribonucleic acid.

Authors:  H N Ananthaswamy; A Eisenstark
Journal:  J Bacteriol       Date:  1977-04       Impact factor: 3.490

9.  Catalase: its effect on microbial enumeration.

Authors:  S E Martin; R S Flowers; Z J Ordal
Journal:  Appl Environ Microbiol       Date:  1976-11       Impact factor: 4.792

10.  Protein expression profiling of lens epithelial cells from Prdx6-depleted mice and their vulnerability to UV radiation exposure.

Authors:  Eri Kubo; Nailia Hasanova; Yukie Tanaka; Nigar Fatma; Yoshihiro Takamura; Dhirendra P Singh; Yoshio Akagi
Journal:  Am J Physiol Cell Physiol       Date:  2009-11-04       Impact factor: 4.249

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