OBJECTIVE: To investigate the nature of deficits in social cognition and real-life decision making in a group of patients with Alzheimer's disease (AD). DESIGN: A comprehensive neuropsychological and psychiatric assessment, including the Moral Judgment Interview and the Bechara's Card Test, was carried out in 25 patients with AD and 20 age-comparable normal controls. SETTING: Outpatient clinic. RESULTS: AD patients had significantly lower scores in the Moral Judgment Interview and obtained significantly less earnings in the card test when compared to the normal control group. The Moral Judgment Interview score correlated significantly with Raven's Progressive Matrices and Block Design, whereas the card test correlated significantly with both the Benton Visual Retention Test and the Buschke Selective Reminding Test. No significant correlations were observed between the experimental tasks and the psychiatric variables. CONCLUSIONS: AD patients demonstrated significant deficits on tasks assessing social cognition and real-life decision making. These impairments correlated with deficits on specific neuropsychological tasks, but not with behavioral problems frequently found in AD patients.
OBJECTIVE: To investigate the nature of deficits in social cognition and real-life decision making in a group of patients with Alzheimer's disease (AD). DESIGN: A comprehensive neuropsychological and psychiatric assessment, including the Moral Judgment Interview and the Bechara's Card Test, was carried out in 25 patients with AD and 20 age-comparable normal controls. SETTING:Outpatient clinic. RESULTS:ADpatients had significantly lower scores in the Moral Judgment Interview and obtained significantly less earnings in the card test when compared to the normal control group. The Moral Judgment Interview score correlated significantly with Raven's Progressive Matrices and Block Design, whereas the card test correlated significantly with both the Benton Visual Retention Test and the Buschke Selective Reminding Test. No significant correlations were observed between the experimental tasks and the psychiatric variables. CONCLUSIONS:ADpatients demonstrated significant deficits on tasks assessing social cognition and real-life decision making. These impairments correlated with deficits on specific neuropsychological tasks, but not with behavioral problems frequently found in ADpatients.
Authors: Andrew R Carr; Pongsatorn Paholpak; Madelaine Daianu; Sylvia S Fong; Michelle Mather; Elvira E Jimenez; Paul Thompson; Mario F Mendez Journal: Neuropsychologia Date: 2015-10-18 Impact factor: 3.139
Authors: Philip D Harvey; Stephanie Cosentino; Rosie Curiel; Terry E Goldberg; Jeffrey Kaye; David Loewenstein; Daniel Marson; David Salmon; Keith Wesnes; Holly Posner Journal: Innov Clin Neurosci Date: 2017-02-01
Authors: Alexander J Beagle; Ali Zahir; Mia Borzello; Andrew S Kayser; Ming Hsu; Bruce L Miller; Joel H Kramer; Winston Chiong Journal: Cortex Date: 2019-10-31 Impact factor: 4.027
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