Literature DB >> 11081589

Incidence of carcinoma in incidental tonsil asymmetry.

M J Syms1, D P Birkmire-Peters, M R Holtel.   

Abstract

OBJECTIVE: To determine the incidence of malignancy in patients with incidentally discovered unilateral tonsillar enlargement with an otherwise normal physical examination. STUDY
DESIGN: A retrospective review of our institution's experience with unilateral tonsillar enlargement.
RESULTS: During a five-year period, 570 patients underwent tonsillectomy at our institution. Of patients undergoing tonsillectomy, 49 patients (8.6%) underwent tonsillectomy with normal mucosa, no lymphadenopathy, and asymmetry of the tonsils. Two (4.8%) of the 49 patients with unilateral enlargement had the presence of malignancy. The two adult patients had B-cell lymphoma. Of all of the patients undergoing tonsillectomy, 0.35% had occult malignancy. In additional, the ability of the clinically assessed size (1+, 2+, 3+, and 4+) to predict volume was evaluated. The clinically assessed size and pathologically measured volume were significantly correlated (R = 0.333, P < .013). In 60.5% of the patients, the clinically assessed size and the pathologically measured volume agreed with the asymmetry reported on physical examination.
CONCLUSION: A relatively high number of tonsillectomies will be performed to yield an approximately 5% positive rate of malignancy within removed tonsils that are asymmetrical with normal mucosa and no cervical adenopathy.

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Year:  2000        PMID: 11081589     DOI: 10.1097/00005537-200011000-00006

Source DB:  PubMed          Journal:  Laryngoscope        ISSN: 0023-852X            Impact factor:   3.325


  9 in total

1.  Can diffusion-weighted imaging distinguish between normal and squamous cell carcinoma of the palatine tonsil?

Authors:  K S S Bhatia; A D King; D K W Yeung; F Mo; A C Vlantis; K-H Yu; J K T Wong; A T Ahuja
Journal:  Br J Radiol       Date:  2010-07-20       Impact factor: 3.039

Review 2.  Malignancy in routine tonsillectomy specimens: a systematic literature review.

Authors:  Malene Sine Rokkjaer; Tejs Ehlers Klug
Journal:  Eur Arch Otorhinolaryngol       Date:  2014-01-31       Impact factor: 2.503

Review 3.  Radiographic imaging of human papillomavirus related carcinomas of the oropharynx.

Authors:  Amanda S Corey; Patricia A Hudgins
Journal:  Head Neck Pathol       Date:  2012-07-03

Review 4.  Indications for tonsillectomy stratified by the level of evidence.

Authors:  Jochen P Windfuhr
Journal:  GMS Curr Top Otorhinolaryngol Head Neck Surg       Date:  2016-12-15

5.  [Histology after tonsillectomy?].

Authors:  A Schrock; M Jakob; T Send; L Heukamp; M Bucheler; F Bootz
Journal:  HNO       Date:  2009-04       Impact factor: 1.284

Review 6.  Tonsillar malignancy in adult patients with peritonsillar abscess: retrospective study of 275 patients and review of the literature.

Authors:  Malene Sine Rokkjaer; Tejs Ehlers Klug
Journal:  Eur Arch Otorhinolaryngol       Date:  2014-07-08       Impact factor: 2.503

7.  Benign Palatine Tonsil Volume Variation Following Bilateral Tonsillectomy in Adults.

Authors:  Alexandra States; Simon Kirby
Journal:  Cureus       Date:  2020-03-16

8.  Epidermoid cyst localized in the palatine tonsil.

Authors:  Keles Erol; Kaplama Mehmet Erkan; Dolen Tolga; Cobanoglu Bengu
Journal:  J Oral Maxillofac Pathol       Date:  2013-01

9.  A Comprehensive Analysis of Histopathologic Examination Results of Tonsillectomy Specimens.

Authors:  Serkan Kayabasi; Omer Hizli; Serkan Cayir; Melike Ordu
Journal:  Cureus       Date:  2020-01-14
  9 in total

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