Literature DB >> 11081540

Onset of coeliac disease during treatment with interferon for chronic hepatitis C.

G Cammarota, L Cuoco, R Cianci, F Pandolfi, G Gasbarrini.   

Abstract

The immunomodulatory properties of interferon may concur to precipitate or worsen an underlying autoimmune disorders. We report the cases of two men who displayed the various features of coeliac disease during a treatment with 4-interferon (in one case associated with ribavirin) for chronic hepatitis C. The patients stopped the interferon treatment and the symptoms and histological disorders improved after a gluten-free diet. Alpha-interferon is available worldwide for treatment of chronic viral hepatitis. Before treatment with this drug, the patients would have to be monitored for coeliac disease.

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Year:  2000        PMID： 11081540     DOI： 10.1016/S0140-6736(00)02880-4

Source DB:  PubMed          Journal:  Lancet        ISSN： 0140-6736            Impact factor:   79.321


  35 in total

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Review 10.  A review of adverse cutaneous drug reactions resulting from the use of interferon and ribavirin.

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