[The time course of the evoked secretion of the mediator quanta in various regions of the frog motor nerve ending].

Apart from the fact that the gradient of the velocity of the AP propagation along the nerve terminal and the intensity of secretion do exist, the kinetics of a quanta transmitter release may also be revealed in different parts of the terminal. The velocity of the propagation and the minimum sympatric delay tend to diminish along with moving away from the myelinated part of axon, whereas the synchronicity of the quanta release rises. The distinctions in the time course of secretion in different parts of the terminal were amplified when the calcium ion concentration in the medium was enhanced. The observed peculiarities of the secretion kinetics in different regions of nerve ending seem to compensate for diminishing of the amplitude of multiquantal endplate current.