Literature DB >> 11079861

Graphically-enabled integration of bioinformatics tools allowing parallel execution.

K H Cheung1, P Miller, A Sherman, S Weston, E Stratmann, M Schultz, M Snyder, A Kumar.   

Abstract

Rapid analysis of large amounts of genomic data is of great biological as well as medical interest. This type of analysis will greatly benefit from the ability to rapidly assemble a set of related analysis programs and to exploit the power of parallel computing. TurboGenomics, which is a software package currently in its alpha-testing phase, allows integration of heterogeneous software components to be done graphically. In addition, the tool is capable of making the integrated components run in parallel. To demonstrate these abilities, we use the tool to develop a Web-based application that allows integrated access to a set of large-scale sequence data analysis programs used by a transposon-insertion based yeast genome project. We also contrast the differences in building such an application with and without using the TurboGenomics software.

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Mesh:

Year:  2000        PMID: 11079861      PMCID: PMC2243957     

Source DB:  PubMed          Journal:  Proc AMIA Symp        ISSN: 1531-605X


  11 in total

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Authors:  L Kruglyak
Journal:  Nat Genet       Date:  1999-06       Impact factor: 38.330

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Journal:  Genome Res       Date:  1999-03       Impact factor: 9.043

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Journal:  J Mol Biol       Date:  1990-10-05       Impact factor: 5.469

4.  Parallelizing genetic linkage analysis: a case study for applying parallel computation in molecular biology.

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Journal:  Comput Biomed Res       Date:  1991-06

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Authors:  J C Venter; M D Adams; G G Sutton; A R Kerlavage; H O Smith; M Hunkapiller
Journal:  Science       Date:  1998-06-05       Impact factor: 47.728

6.  Base-calling of automated sequencer traces using phred. II. Error probabilities.

Authors:  B Ewing; P Green
Journal:  Genome Res       Date:  1998-03       Impact factor: 9.043

7.  Exploring the metabolic and genetic control of gene expression on a genomic scale.

Authors:  J L DeRisi; V R Iyer; P O Brown
Journal:  Science       Date:  1997-10-24       Impact factor: 47.728

8.  Design and implementation of a CORBA-based genome mapping system prototype.

Authors:  J Hu; C Mungall; D Nicholson; A L Archibald
Journal:  Bioinformatics       Date:  1998       Impact factor: 6.937

9.  Complexity of protein folding.

Authors:  A S Fraenkel
Journal:  Bull Math Biol       Date:  1993-11       Impact factor: 1.758

10.  An integrated web interface for large-scale characterization of sequence data.

Authors:  K H Cheung; A Kumar; M Snyder; P Miller
Journal:  Funct Integr Genomics       Date:  2000-05       Impact factor: 3.410

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