Literature DB >> 1107909

Topical 5-fluorouracil in the treatment of carcinoma in situ of the vulva.

T E Carson, W J Hoskins, J F Wurzel.   

Abstract

The clinical and pathologic response of carcinoma in situ of the vulva in a 42-year-old woman treated with topical 5-fluorouracil is reported. Except for one persistent area of involvement in the anal region which required local excision, the result of treatment was excellent, with no evidence of recurrence after 2 years' followup. This important adjunct in the treatment of intra-epithelial carcinoma deserves long-range investigation.

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Year:  1976        PMID: 1107909

Source DB:  PubMed          Journal:  Obstet Gynecol        ISSN: 0029-7844            Impact factor:   7.661


  1 in total

1.  Phototoxicity of 5-aminolevulinic acid in the HeLa cell line as an indicative measure of photodynamic effect after topical administration to gynecological lesions of intraepithelial form.

Authors:  Paul A McCarron; Ryan F Donnelly; Brendan F Gilmore; A David Woolfson; Raymond McClelland; Agnieszka Zawislak; John H Price
Journal:  Pharm Res       Date:  2004-10       Impact factor: 4.200

  1 in total

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