Literature DB >> 11078203

L-Selenohomocysteine: one-step synthesis from L-selenomethionine and kinetic analysis as substrate for methionine synthases.

Z S Zhou1, A E Smith, R G Matthews.   

Abstract

A single-step convenient synthesis of L-selenohomocysteine (SeHcy) from L-selenomethionine (SeMet) using sodium in liquid ammonia is described. Methionine synthases convert SeHcy to SeMet at rates comparable to their rates of conversion of L-homocysteine (Hcy) to L-methionine (Met). This study suggests that SeHcy generated from SeMet metabolism can be efficiently recycled to SeMet in mammals.

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Year:  2000        PMID： 11078203     DOI： 10.1016/s0960-894x(00)00498-4

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  11 in total

1.  Synthesis and characterization of Se-adenosyl-L-selenohomocysteine selenoxide.

Authors:  Richard I Duclos; Dillon C Cleary; Kalli C Catcott; Zhaohui Sunny Zhou
Journal:  J Sulphur Chem       Date:  2015-04-01       Impact factor: 2.680

2.  Trans-sulfuration Pathway Seleno-amino Acids Are Mediators of Selenomethionine Toxicity in Saccharomyces cerevisiae.

Authors:  Myriam Lazard; Marc Dauplais; Sylvain Blanquet; Pierre Plateau
Journal:  J Biol Chem       Date:  2015-03-05       Impact factor: 5.157

3.  Detection and quantitation of succinimide in intact protein via hydrazine trapping and chemical derivatization.

Authors:  Joshua J Klaene; Wenqin Ni; Joshua F Alfaro; Zhaohui Sunny Zhou
Journal:  J Pharm Sci       Date:  2014-07-14       Impact factor: 3.534

4.  Discovery of undefined protein cross-linking chemistry: a comprehensive methodology utilizing 18O-labeling and mass spectrometry.

Authors:  Min Liu; Zhongqi Zhang; Tianzhu Zang; Chris Spahr; Janet Cheetham; Da Ren; Zhaohui Sunny Zhou
Journal:  Anal Chem       Date:  2013-05-28       Impact factor: 6.986

5.  Large-scale, protection-free synthesis of Se-adenosyl-L-selenomethionine analogues and their application as cofactor surrogates of methyltransferases.

Authors:  Ian R Bothwell; Minkui Luo
Journal:  Org Lett       Date:  2014-05-22       Impact factor: 6.005

6.  Discovery of a chemical modification by citric acid in a recombinant monoclonal antibody.

Authors:  Chris Chumsae; Liqiang Lisa Zhou; Yang Shen; Jessica Wohlgemuth; Emma Fung; Randall Burton; Czeslaw Radziejewski; Zhaohui Sunny Zhou
Journal:  Anal Chem       Date:  2014-08-27       Impact factor: 6.986

7.  Comparison of Protein N-Homocysteinylation in Rat Plasma under Elevated Homocysteine Using a Specific Chemical Labeling Method.

Authors:  Tianzhu Zang; Ligi Paul Pottenplackel; Diane E Handy; Joseph Loscalzo; Shujia Dai; Richard C Deth; Zhaohui Sunny Zhou; Jisheng Ma
Journal:  Molecules       Date:  2016-09-08       Impact factor: 4.411

8.  Metabolic Pathway Profiling in Intracellular and Extracellular Environments of Streptococcus thermophilus During pH-Controlled Batch Fermentations.

Authors:  Yali Qiao; Gefei Liu; Xuepeng Lv; Xuejing Fan; Yanjiao Zhang; Li Meng; Mingzhi Ai; Zhen Feng
Journal:  Front Microbiol       Date:  2020-01-21       Impact factor: 5.640

Review 9.  Selenomethionine: A Pink Trojan Redox Horse with Implications in Aging and Various Age-Related Diseases.

Authors:  Muhammad Jawad Nasim; Mhd Mouayad Zuraik; Ahmad Yaman Abdin; Yannick Ney; Claus Jacob
Journal:  Antioxidants (Basel)       Date:  2021-05-31

10.  Discovery and characterization of a photo-oxidative histidine-histidine cross-link in IgG1 antibody utilizing ¹⁸O-labeling and mass spectrometry.

Authors:  Min Liu; Zhongqi Zhang; Janet Cheetham; Da Ren; Zhaohui Sunny Zhou
Journal:  Anal Chem       Date:  2014-05-02       Impact factor: 6.986
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