| Literature DB >> 11078199 |
H Kitajima1, M Nakamura, H Tamakawa, N Goto.
Abstract
Hybrid compounds of non-sulfonylurea insulinotropic agents and thiazolidinedione-derived insulin-sensitizing agents were designed and synthesized. The benzylidenesuccinic acid derivative 24 was equal both to nateglinide in potency of insulin-releasing activity and to pioglitazone in insulin-sensitizing activity.Entities:
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Year: 2000 PMID： 11078199 DOI： 10.1016/s0960-894x(00)00491-1
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823