| Literature DB >> 11078191 |
Y J Kim1, D A Kaiser, T D Pollard, Y Ichikawa.
Abstract
A decamer of a beta-amino acid analogue of L-proline, (3R)-carboxy pyrrolidine (beta-proline), was synthesized from a readily available (R)-glycidol. It was found to possess a rigid secondary structure, as evidenced by its CD spectrum. The beta-proline decamer, however, failed to bind to profilin, whereas the corresponding alpha-L-proline decamer bound tightly to this protein.Entities:
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Year: 2000 PMID： 11078191 DOI： 10.1016/s0960-894x(00)00486-8
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823