| Literature DB >> 11077172 |
S Bani1, A Kaul, B S Jaggi, K A Suri, O P Suri, O P Sharma.
Abstract
The hydrosoluble fraction of Euphorbia royleana latex (AER), administered by gavage at doses of 50-200 mg/kg, showed dose-dependent anti-inflammatory and anti-arthritic effects in different acute and chronic test models in rats and mice. It reduced the exudate volume and the migration of leukocytes and showed a poor inhibitory effect on the granuloma formation induced by cotton pellets, while it had a low ulcerogenic score. The oral LD(50) was more than 1500 mg/kg in both rats and mice.Entities:
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Year: 2000 PMID： 11077172 DOI： 10.1016/s0367-326x(00)00225-2
Source DB: PubMed Journal: Fitoterapia ISSN： 0367-326X Impact factor: 2.882