Literature DB >> 11076576

CR377, a new pentaketide antifungal agent isolated from an endophytic fungus.

S F Brady1, J Clardy.   

Abstract

Cultures of endophytic fungi collected in the Guanacaste Conservation Area of Costa Rica were screened for antifungal activity. CR377, a new pentaketide antifungal agent, was isolated from the culture broth of a fungus, CR377 (Fusarium sp.), that showed potent activity against Candida albicans in this assay. The structure of CR377 was established using 1- and 2-D NMR and HRFABMS.

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Year:  2000        PMID： 11076576     DOI： 10.1021/np990568p

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  18 in total

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