Literature DB >> 11076574

Lyngbyabellin B, a toxic and antifungal secondary metabolite from the marine cyanobacterium Lyngbya majuscula.

K E Milligan1, B L Marquez, R T Williamson, W H Gerwick.   

Abstract

Lyngbyabellin B (1) was isolated from a marine cyanobacterium, Lyngbya majuscula, collected near the Dry Tortugas National Park, Florida. This new cyclic depsipeptide displayed potent toxicity toward brine shrimp and the fungus Candida albicans. The planar structure was deduced using 1D and 2D NMR spectroscopic methods, and the stereochemistry is proposed through a combination of NMR and chiral GC/MS analysis.

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Year:  2000        PMID： 11076574     DOI： 10.1021/np000133y

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  16 in total

Review 1.  Marine pharmacology in 2000: marine compounds with antibacterial, anticoagulant, antifungal, anti-inflammatory, antimalarial, antiplatelet, antituberculosis, and antiviral activities; affecting the cardiovascular, immune, and nervous systems and other miscellaneous mechanisms of action.

Authors:  Alejandro M S Mayer; Mark T Hamann
Journal:  Mar Biotechnol (NY)       Date:  2003-11-03       Impact factor: 3.619

2.  Apratoxin H and apratoxin A sulfoxide from the Red Sea cyanobacterium Moorea producens.

Authors:  Christopher C Thornburg; Elise S Cowley; Justyna Sikorska; Lamiaa A Shaala; Jane E Ishmael; Diaa T A Youssef; Kerry L McPhail
Journal:  J Nat Prod       Date:  2013-09-09       Impact factor: 4.050

3.  Scytonemides A and B, cyclic peptides with 20S proteasome inhibitory activity from the cultured cyanobacterium Scytonema hofmanii.

Authors:  Aleksej Krunic; Armelle Vallat; Shunyan Mo; Daniel D Lantvit; Steven M Swanson; Jimmy Orjala
Journal:  J Nat Prod       Date:  2010-11-08       Impact factor: 4.050

Review 4.  Marine natural product peptides with therapeutic potential: Chemistry, biosynthesis, and pharmacology.

Authors:  Vedanjali Gogineni; Mark T Hamann
Journal:  Biochim Biophys Acta Gen Subj       Date:  2017-08-24       Impact factor: 3.770

5.  Pharmacology and toxicology of pahayokolide A, a bioactive metabolite from a freshwater species of Lyngbya isolated from the Florida Everglades.

Authors:  John P Berry; Miroslav Gantar; Robert E Gawley; Minglei Wang; Kathleen S Rein
Journal:  Comp Biochem Physiol C Toxicol Pharmacol       Date:  2004-12       Impact factor: 3.228

6.  Cytotoxic halogenated macrolides and modified peptides from the apratoxin-producing marine cyanobacterium Lyngbya bouillonii from Guam.

Authors:  Susan Matthew; Lilibeth A Salvador; Peter J Schupp; Valerie J Paul; Hendrik Luesch
Journal:  J Nat Prod       Date:  2010-09-24       Impact factor: 4.050

Review 7.  Integrating mass spectrometry and genomics for cyanobacterial metabolite discovery.

Authors:  Nathan A Moss; Matthew J Bertin; Karin Kleigrewe; Tiago F Leão; Lena Gerwick; William H Gerwick
Journal:  J Ind Microbiol Biotechnol       Date:  2015-11-17       Impact factor: 3.346

8.  Cyanobacteria, Lyngbya aestuarii and Aphanothece bullosa as antifungal and antileishmanial drug resources.

Authors:  Maheep Kumar; Manoj Kumar Tripathi; Akanksha Srivastava; Jalaj Kumar Gour; Rakesh Kumar Singh; Ragini Tilak; Ravi Kumar Asthana
Journal:  Asian Pac J Trop Biomed       Date:  2013-06

9.  Biologically active new metabolites from a Florida collection of Moorea producens.

Authors:  Omar M Sabry; Douglas E Goeger; William H Gerwick
Journal:  Nat Prod Res       Date:  2016-07-18       Impact factor: 2.861

Review 10.  Marine cyanobacteria compounds with anticancer properties: a review on the implication of apoptosis.

Authors:  Margarida Costa; João Costa-Rodrigues; Maria Helena Fernandes; Piedade Barros; Vitor Vasconcelos; Rosário Martins
Journal:  Mar Drugs       Date:  2012-09-28       Impact factor: 6.085
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