Literature DB >> 11076351

[Irradiation of cornea with ultraviolet light and riboflavin administration as a new treatment for erosive corneal processes, preliminary results in four patients].

E Schnitzler1, E Spörl, T Seiler.   

Abstract

BACKGROUND: Corneal melting is a serious condition and in many cases maybe managed only by surgery. UV-radiation with Riboflavin is a new method that may stop the melting process of the cornea. PATIENTS AND
METHOD: Four patients suffering from melting ulcera of the cornea of various origin underwent a single UV-radiation. Two ultraviolet diodes were used emitting light with an wavelength of 370 nm with an energy of 2.5 mW/cm2. The radiation time was 30 minutes. Before he radiation was performed 2-3 drops of 0.11% Riboflavinsolution were applied to the cornea. The treatment area was 6-7 mm in diameter.
RESULTS: After the treatment in three of the four patients the melting process of the cornea stopped. At least temporarily, a surgical procedure could be delayed.
CONCLUSION: Because of the absence of any side-effects in serious cases the method is recommended prior to surgery.

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Year:  2000        PMID: 11076351     DOI: 10.1055/s-2000-10344

Source DB:  PubMed          Journal:  Klin Monbl Augenheilkd        ISSN: 0023-2165            Impact factor:   0.700


  24 in total

Review 1.  [Complications of corneal cross-linking].

Authors:  T G Seiler; G Schmidinger; I Fischinger; T Koller; T Seiler
Journal:  Ophthalmologe       Date:  2013-07       Impact factor: 1.059

Review 2.  Corneal collagen crosslinking in keratoconus and other eye disease.

Authors:  Adel Alhayek; Pei-Rong Lu
Journal:  Int J Ophthalmol       Date:  2015-04-18       Impact factor: 1.779

3.  Comparative proteomic analysis of amnion membrane transplantation and cross-linking treatments in an experimental alkali injury model.

Authors:  Sevgi Subasi; Ozgul Altintas; Murat Kasap; Nil Guzel; Gurler Akpinar; Suleyman Karaman
Journal:  Int Ophthalmol       Date:  2017-11-23       Impact factor: 2.031

4.  Collagen cross-linking for resistant corneal ulcer.

Authors:  Rana Sorkhabi; Mohamadreza Sedgipoor; Ali Mahdavifard
Journal:  Int Ophthalmol       Date:  2012-09-27       Impact factor: 2.031

5.  UVA-riboflavin photochemical therapy of bacterial keratitis: a pilot study.

Authors:  Karim Makdoumi; Jes Mortensen; Omid Sorkhabi; Bo-Eric Malmvall; Sven Crafoord
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2011-08-27       Impact factor: 3.117

6.  Corneal collagen cross-linking.

Authors:  Mirko R Jankov Ii; Vesna Jovanovic; Ljubisa Nikolic; Jonathan C Lake; Georgos Kymionis; Efekan Coskunseven
Journal:  Middle East Afr J Ophthalmol       Date:  2010-01

7.  Evaluation of antibacterial efficacy of photo-activated riboflavin using ultraviolet light (UVA).

Authors:  Karim Makdoumi; Anders Bäckman; Jes Mortensen; Sven Crafoord
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2009-11-18       Impact factor: 3.117

8.  Corneal Collagen Cross-linking for Treatment of Bacterial and Herpetic Keratitis.

Authors:  Mohammad Reza Khalili; Hamid Reza Jahadi; Mashaallah Karimi; Masoud Yasemi
Journal:  J Clin Diagn Res       Date:  2017-07-01

9.  Collagen crosslinking with photoactivated riboflavin in advanced infectious keratitis with corneal melting: Electrophysiological Study.

Authors:  Eman A Awad; Mona Abdelkader; Ameera G Abdelhameed; Walid M Gaafar; Tharwat H Mokbel
Journal:  Int J Ophthalmol       Date:  2020-04-18       Impact factor: 1.779

10.  Evaluation of the efficacy of excimer laser ablation of cross-linked porcine cornea.

Authors:  Shihao Chen; Yini Li; Aleksander Stojanovic; Jia Zhang; Yibo Wang; Qinmei Wang; Theo Seiler
Journal:  PLoS One       Date:  2012-10-03       Impact factor: 3.240

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