| Literature DB >> 110759 |
R M Stroshane, J A Chan, E A Rubalcaba, A L Garretson, A A Aszalos, P P Roller.
Abstract
Three antibiotics possessing cytotoxic properties were isolated from a strain of Streptomyces griseus (FCRC-57). One was found to be identical with griseorhodin A. A second, FCRC-57-U, was found to be identical to griseorhodin C. FCRC-57-G is a new antibiotic structurally related to griseorhodins A and C, and is active against KB cells in vitro. The structure of this new antibiotic was determined using mass spectrometry, proton and carbon nuclear magnetic resonance spectroscopy and synthesis.Entities:
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Year: 1979 PMID： 110759 DOI： 10.7164/antibiotics.32.197
Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN： 0021-8820 Impact factor: 2.649